ADHDgene Database

SNP Report

Basic Info

Name	rs2122643 dbSNP Ensembl
Location	Chr4:62654938(Fwd)
Variant Alleles	T/A
Ancestral Allele	A
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000512091; ENST00000514591; ENST00000509896; ENST00000511324; ENST00000506700; ENST00000507164; ENST00000508693; ENST00000507625; ENST00000514157; ENST00000506720; ENST00000504896; ENST00000508946; ENST00000514996; ENST00000506746; ENST00000545650; ENST00000570545; ENST00000574812; ENST00000576325; ENST00000574919; ENST00000573738; ENST00000577151; ENST00000572342; ENST00000573960; ENST00000576469; ENST00000574839; ENST00000572079; ENST00000576028; ENST00000571630; ENST00000573720)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases M, 2011			allelic P-value=0.032, OR=1.31 for all ADHD, allelic P-value...... allelic P-value=0.032, OR=1.31 for all ADHD, allelic P-value=0.034, OR=1.32 for combined ADHD; genotypic P-value=0.018, OR=1.45 for all ADHD, genotypic P-value=0.53 for combined ADHD More...	nominal association with ADHD and associated with combined A...... nominal association with ADHD and associated with combined ADHD, but cannot survive the correction for multiple testing More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
LPHN3	latrophilin 3	4q13.1	4(3/0/1)

SNPs in LD with rs2122643 (count: 15) View in gBrowse (chr4:62637158..62688669 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs2345047	downstream_gene_variant; intron_variant	1.0[CEU]; 0.934[CHB]; 1.0[JPT]; 1.0[YRI]
rs10015258	intron_variant; upstream_gene_variant	0.955[CEU]; 0.94[CHB]; 1.0[JPT]; 0.826[YRI]
rs1901220	intron_variant	0.922[YRI]
rs4493573	intron_variant	1.0[CEU]; 0.871[CHB]
rs1817052	intron_variant	1.0[CEU]
rs7656882	intron_variant	1.0[CEU]; 0.804[CHB]
rs12509742	intron_variant; upstream_gene_variant	1.0[CEU]
rs2122640	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs2345044	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.922[YRI]
rs2345045	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.922[YRI]
rs1376307	intron_variant	1.0[CEU]
rs2345049	downstream_gene_variant; intron_variant	0.849[CEU]; 0.934[CHB]; 1.0[JPT]
rs1901223	intron_variant	0.96[CEU]
rs2345043	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs4860434	intron_variant	1.0[CEU]