ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs17673653 dbSNP Ensembl
Location	Chr5:170166594(Fwd)
Variant Alleles	A/T
Ancestral Allele	A
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000520740; ENST00000377360; ENST00000328939; ENST00000390656; ENST00000411494; ENST00000434108)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lantieri F, 2010	T:A		Binomial P-value=0.34, OR=0.94 for whole sample; Binomial P-...... Binomial P-value=0.34, OR=0.94 for whole sample; Binomial P-value=0.75, OR=1.11 for C-subtype More...	no significant association no significant association	Non-significant
Neale BM, 2008	T:A		Uncorrected TDT P-value=4.32E-05 (OR=0.6612) Uncorrected TDT P-value=4.32E-05 (OR=0.6612)	One of top 25 results in uncorrected TDT test One of top 25 results in uncorrected TDT test	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 0)

Genes from other sources (count: 1)

Approved Symbol	Approved Name	Location
KCNIP1	Kv channel interacting protein 1	5q35

SNPs in LD with rs17673653 (count: 45) View in gBrowse (chr5:170121808..170168804 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 1)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1541665	intron_variant	2(0/2/0)	1.0[CEU]; 0.93[CHB]; 0.931[GIH]; 0.825[JPT]; 0.862[MEX]; 0.888[TSI]

LD-proxies (count: 44)

rs_ID	Functional Annotation	r²[population]
rs329474	intron_variant	0.91[JPT]
rs4868017	intron_variant	0.89[CEU]; 0.93[CHB]; 0.91[JPT]
rs1363715	downstream_gene_variant	0.824[CEU]; 1.0[CHB]; 1.0[JPT]
rs10475952	intron_variant	0.886[CEU]; 1.0[CHB]; 1.0[JPT]
rs2032863	intron_variant	1.0[CEU]; 1.0[CHB]; 0.906[GIH]; 1.0[JPT]; 0.907[MEX]; 0.889[TSI]
rs2277952	intron_variant	0.91[JPT]
rs6879997	intron_variant	1.0[JPT]
rs50057	intron_variant	0.91[JPT]
rs6870201	intron_variant	1.0[JPT]
rs905818	intron_variant	0.89[CEU]; 0.812[CHB]; 0.847[GIH]
rs9313520	intron_variant	0.89[CEU]; 1.0[CHB]; 0.91[JPT]
rs7733559	intron_variant	0.91[JPT]
rs2277951	intron_variant	0.888[CEU]; 1.0[CHB]; 0.909[GIH]; 0.91[JPT]
rs872436	intron_variant	0.882[CEU]; 0.867[CHB]; 0.825[JPT]; 0.808[TSI]
rs11134648	downstream_gene_variant	1.0[JPT]
rs4464713	intron_variant	0.93[CHB]; 0.91[JPT]
rs1363709	intron_variant	1.0[CEU]; 0.918[CHB]; 0.813[JPT]
rs1055381	3_prime_UTR_variant; downstream_gene_variant	1.0[JPT]
rs1363713	3_prime_UTR_variant; downstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.906[MEX]; 0.877[TSI]
rs905817	intron_variant	1.0[CEU]; 0.867[CHB]; 0.931[GIH]; 0.825[JPT]; 0.907[MEX]; 0.889[TSI]
rs329472	intron_variant	0.91[JPT]
rs2216654		0.824[JPT]
rs7713498	intron_variant	0.825[JPT]
rs1363711	intron_variant	1.0[JPT]
rs2194162	intron_variant	1.0[CEU]; 0.867[CHB]; 0.825[JPT]
rs4867628	intron_variant	0.842[CEU]; 1.0[CHB]; 1.0[JPT]
rs6890273	downstream_gene_variant	1.0[JPT]
rs10045333	intron_variant	0.89[CEU]; 0.867[CHB]; 0.825[JPT]
rs4349730	intron_variant	0.89[CEU]; 0.93[CHB]; 0.825[JPT]
rs905816	intron_variant	0.91[JPT]
rs6894316	intron_variant	0.91[JPT]
rs6887850	intron_variant	1.0[JPT]
rs872435	intron_variant	1.0[CEU]; 0.867[CHB]; 0.93[GIH]; 0.825[JPT]; 0.907[MEX]; 0.889[TSI]
rs10462999	intron_variant	0.933[CEU]; 1.0[CHB]; 0.91[JPT]
rs329476	intron_variant	0.91[JPT]
rs1363714	downstream_gene_variant	0.889[CEU]; 1.0[CHB]; 1.0[JPT]
rs4041562	intron_variant	1.0[CEU]; 0.93[CHB]; 0.825[JPT]
rs6872337	downstream_gene_variant	1.0[JPT]
rs1422978	intron_variant	1.0[JPT]
rs1592987	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs4867629	downstream_gene_variant	0.83[CEU]; 1.0[CHB]; 0.929[GIH]; 1.0[JPT]; 0.907[MEX]; 0.841[TSI]
rs11134647	intron_variant	0.842[CEU]; 1.0[CHB]; 1.0[JPT]
rs102686	intron_variant	0.91[JPT]
rs984559	intron_variant	1.0[CEU]; 0.93[CHB]; 0.931[GIH]; 0.825[JPT]; 0.907[MEX]; 0.889[TSI]