ADHDgene Database

SNP Report

Basic Info

Name	rs12317552 dbSNP Ensembl
Location	Chr12:63040610(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000228705) downstream_gene_variant(ENST00000551214) upstream_gene_variant(ENST00000459527)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	T:C		GLM P-value=9.14E-06, meta-analysis P-value=0.005663 GLM P-value=9.14E-06, meta-analysis P-value=0.005663	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H	12q14.1	1(0/0/1)

SNPs in LD with rs12317552 (count: 7) View in gBrowse (chr12:63010175..63050251 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs10506445	downstream_gene_variant; intron_variant; nc_transcript_variant	1(0/1/0)	0.879[CEU]; 1.0[GIH]

rs_ID	Functional Annotation	r²[population]
rs17098139	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]
rs12317548	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant	0.806[ASW]; 1.0[CHB]; 1.0[CHD]; 0.883[YRI]
rs17732506	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant	1.0[CEU]
rs7135127	downstream_gene_variant	1.0[CHB]
rs17676109	intron_variant; nc_transcript_variant; upstream_gene_variant	0.879[CEU]
rs12297799	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant	1.0[CHB]; 0.96[YRI]