ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs11954894 dbSNP Ensembl
Location	chr5:50674131(Fwd)
Variant Alleles	C/A/T
Ancestral Allele	C
Functional Annotation	downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000558403) nc_transcript_variant(ENST00000559112; ENST00000601500) non_coding_exon_variant(ENST00000559112; ENST00000601500) upstream_gene_variant(ENST00000230658)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Laurin N, 2008(a)	C/T		P-value=0.079 in the catergorical analysis, P-value>0.05 in ...... P-value=0.079 in the catergorical analysis, P-value>0.05 in the quantitative analysis More...	no significant evidence of association no significant evidence of association	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ISL1	ISL LIM homeobox 1	5q11.2	1(0/1/0)

Genes from other sources (count: 0)

SNPs in LD with rs11954894 (count: 40) View in gBrowse (chr5:50583089..50791584 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 40)

rs_ID	Functional Annotation	r²[population]
rs12521818		0.825[CEU]
rs963195	downstream_gene_variant	0.834[CEU]
rs9291739		0.829[CEU]
rs9291732		0.825[CEU]
rs6864170	nc_transcript_variant; non_coding_exon_variant	0.957[CEU]; 1.0[CHB]; 0.824[JPT]
rs9291777	upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.825[JPT]
rs7446508		0.873[CEU]
rs2897069		0.825[CEU]
rs16878735		0.826[CEU]
rs7708866	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs7722654		1.0[CEU]; 1.0[CHB]; 0.824[JPT]
rs2161592		0.955[CEU]
rs10053849		0.955[CEU]
rs17398816		0.825[CEU]
rs9291750		0.829[CEU]
rs10038485		0.834[CEU]
rs9291746	downstream_gene_variant	0.834[CEU]
rs11747876		0.955[CEU]
rs1559279		0.958[CEU]
rs10045426	downstream_gene_variant	0.834[CEU]
rs11745678		0.826[CEU]
rs1559280		0.957[CEU]
rs7719442	upstream_gene_variant	0.955[CEU]; 1.0[CHB]; 0.811[JPT]
rs10038557	downstream_gene_variant	0.825[CEU]
rs2059224		0.957[CEU]
rs16875094		1.0[CEU]; 1.0[CHB]; 0.824[JPT]
rs2161591		0.958[CEU]
rs10052407		0.834[CEU]
rs7711781		0.825[CEU]
rs3811911	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.811[JPT]; 0.893[YRI]
rs6867226	downstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.811[JPT]; 0.839[YRI]
rs9283702	intron_variant; nc_transcript_variant	0.958[CEU]; 1.0[CHB]; 0.824[JPT]
rs10061466		0.958[CEU]; 1.0[CHB]; 0.825[JPT]
rs4865656		0.825[JPT]
rs2115322	downstream_gene_variant	0.897[JPT]
rs3792733	intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.81[JPT]
rs10471584	downstream_gene_variant	1.0[CEU]; 0.824[CHB]
rs2217314	downstream_gene_variant	0.825[CEU]
rs6899166		0.958[CEU]
rs10471549	downstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]