ADHDgene Database

SNP Report

Basic Info

Name	rs11594082 dbSNP Ensembl
Location	Chr10:73299253(Fwd)
Variant Alleles	G/T/-
Ancestral Allele	G
Functional Annotation	feature_truncation; intron_variant; nc_transcript_variant.
Consequence to Transcript	feature_truncation(ENST00000461841; ENST00000299366; ENST00000224721; ENST00000398809; ENST00000398842) intron_variant(ENST00000461841; ENST00000299366; ENST00000224721; ENST00000398809; ENST00000398842) nc_transcript_variant(ENST00000461841)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lesch KP, 2008			ANOVA P-value=1.00E-05, Mean of ranks=52 ANOVA P-value=1.00E-05, Mean of ranks=52	one of the top 30 single SNPs located in gene regions (inclu...... one of the top 30 single SNPs located in gene regions (including 100kb of flanking sequences) ranked according to the mean rank calculated across three statistics More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
CDH23	cadherin-related 23	10q22.1	1(0/1/0)

SNPs in LD with rs11594082 (count: 3) View in gBrowse (chr10:73286290..73299253 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs11594877	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[GIH]; 0.966[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs16929022	intron_variant; nc_transcript_variant	1.0[CEU]
rs17634834	intron_variant; nc_transcript_variant	0.824[MEX]