ADHDgene Database

SNP Report

Basic Info

Name	rs11175219 dbSNP Ensembl
Location	Chr12:64362719(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000357825; ENST00000355086; ENST00000537556) nc_transcript_variant(ENST00000537556)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Stergiakouli E., 2012	T/C	T	P=0.0000106, OR=1.46, 95% CI=1.23-1.73 P=0.0000106, OR=1.46, 95% CI=1.23-1.73	One of the top 25 independent SNP in this ADHD GWAS. One of the top 25 independent SNP in this ADHD GWAS.	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	12q13.13	1(0/0/1)

SNPs in LD with rs11175219 (count: 5) View in gBrowse (chr12:64336805..64536009 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs17711166	intron_variant; nc_transcript_variant	1.0[ASW]
rs789738	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[ASW]
rs17099949	intron_variant; nc_transcript_variant	1.0[ASW]
rs12227635	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs699629	intron_variant; upstream_gene_variant	1.0[ASW]