ADHDgene Database

SNP Report

Basic Info

Name	rs10879352 dbSNP Ensembl
Location	chr12:72406958(Fwd)
Variant Alleles	T/C
Ancestral Allele	C
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000333850)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Oades RD, 2008			P-value=0.015048; FDR P-value=0.06598 for cognitive impulsiv...... P-value=0.015048; FDR P-value=0.06598 for cognitive impulsivity More...	attained nominal significance for an association with cognit...... attained nominal significance for an association with cognitive impulsivity More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
TPH2	tryptophan hydroxylase 2	12q15	11(8/3/0)

SNPs in LD with rs10879352 (count: 10) View in gBrowse (chr12:72353257..72407477 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs10879351	intron_variant	0.88[CEU]; 0.888[ASW]; 0.827[YRI]
rs7967686	intron_variant	0.809[CEU]
rs9325202	intron_variant	1.0[CEU]; 0.955[TSI]; 0.943[ASW]; 1.0[CHB]; 0.954[CHD]; 0.949[JPT]; 0.948[GIH]; 0.954[MEX]; 0.906[MKK]; 0.964[YRI]
rs11179039	intron_variant	0.88[CEU]; 0.888[ASW]
rs12322900	intron_variant; nc_transcript_variant	0.829[CEU]
rs10748190	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.964[YRI]
rs7969114	intron_variant	0.819[CEU]
rs3903502	intron_variant	1.0[CEU]; 1.0[ASW]; 1.0[CHB]; 1.0[JPT]; 0.974[GIH]; 0.813[LWK]; 0.954[MEX]
rs10506646	intron_variant	1.0[JPT]
rs1352251	intron_variant	0.826[CHB]; 0.895[YRI]