ADHDgene Database

SNP Report

Basic Info

Name	rs10823954 dbSNP Ensembl
Location	Chr10:53773365(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000373985; ENST00000373980; ENST00000373976; ENST00000401604)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	A:G		GLM P-value=3.01E-05, meta-analysis P-value=0.02442 GLM P-value=3.01E-05, meta-analysis P-value=0.02442	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PRKG1	protein kinase, cGMP-dependent, type I	10q11.2	1(0/0/1)

SNPs in LD with rs10823954 (count: 36) View in gBrowse (chr10:53707749..53790461 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1903960	intron_variant	1(0/1/0)	0.873[CEU]; 0.838[TSI]
rs10823978	intron_variant	1(0/1/0)	0.873[CEU]; 1.0[CHB]; 0.906[GIH]; 0.827[MEX]; 0.918[TSI]; 0.919[YRI]
rs7893146	intron_variant	1(0/1/0)	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.956[MEX]; 0.827[MKK]; 1.0[TSI]
rs1903979	intron_variant	1(0/1/0)	1.0[CHB]; 0.971[CHD]; 1.0[JPT]; 0.827[MKK]
rs7092969	intron_variant	1(0/0/1)	0.832[CEU]; 0.839[TSI]
rs1903977	intron_variant	1(0/0/1)	1.0[CHB]; 0.941[CHD]; 1.0[JPT]; 0.827[MKK]