ADHDgene Database

SNP Report

Basic Info

Name	rs1012053 dbSNP Ensembl
Location	chr13:42653437(Fwd)
Variant Alleles	C/A
Ancestral Allele	A
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000261491; ENST00000337343; ENST00000379274; ENST00000540693)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Schimmelmann, B. G.,2013			Nominal two-sided P-value=0.396 (OR=0.92;95%CI=0.74-1.12) Nominal two-sided P-value=0.396 (OR=0.92;95%CI=0.74-1.12)	No evidence for association was found with ADHD for the rema...... No evidence for association was found with ADHD for the remaining eight SNPs, which were found to be genome-wide significant for BD in international GWAS More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DGKH	diacylglycerol kinase, eta	13q13.3	2(1/1/0)

SNPs in LD with rs1012053 (count: 16) View in gBrowse (chr13:42642810..42701941 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs670676	intron_variant	0.812[TSI]; 0.849[GIH]; 0.905[MEX]
rs9525566	intron_variant; nc_transcript_variant; non_coding_exon_variant	0.954[CHB]; 0.905[JPT]
rs1170183	intron_variant	0.861[ASW]; 0.954[CHB]; 1.0[CHD]; 0.953[JPT]; 0.915[GIH]; 0.828[MEX]
rs9532987	intron_variant; upstream_gene_variant	0.865[CHB]; 0.824[JPT]
rs2253650	intron_variant	1.0[CEU]; 1.0[TSI]; 1.0[ASW]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]; 1.0[GIH]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[YRI]
rs9315885	downstream_gene_variant; intron_variant	0.868[CHB]; 0.824[JPT]
rs1170187	intron_variant	0.813[TSI]; 0.854[GIH]; 0.905[MEX]; 0.829[MKK]
rs9532989	intron_variant; upstream_gene_variant	0.868[CHB]; 0.824[JPT]
rs681657	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs9532985	intron_variant; nc_transcript_variant; non_coding_exon_variant	0.861[ASW]; 0.954[CHB]; 1.0[CHD]; 0.953[JPT]; 0.915[GIH]; 0.828[MEX]
rs7990452	intron_variant; upstream_gene_variant	0.868[CHB]; 0.824[JPT]
rs1170188	intron_variant	0.813[TSI]; 0.814[CHD]; 0.854[GIH]; 0.905[MEX]; 0.858[MKK]
rs1170158	intron_variant	0.813[TSI]; 0.854[GIH]; 0.905[MEX]
rs1177637	intron_variant	0.813[TSI]; 0.854[GIH]; 0.905[MEX]; 0.829[MKK]
rs4142112	intron_variant; upstream_gene_variant	0.868[CHB]; 0.82[JPT]
rs669642	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.849[YRI]