ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa00030
Name Pentose phosphate pathway
Description  The pentose phosphate pathway is a process of glucose turnover that produces NADPH as reducing equivalents and pentoses as essential parts of nucleotides. There are two different phases in the pathway. One is irreversible oxidative phase in which glucose-6P is converted to ribulose-5P by oxidative decarboxylation, and NADPH is generated [MD:M00006]. The other is reversible non-oxidative phase in which phosphorylated sugars are interconverted to generate xylulose-5P, ribulose-5P, and ribose-5P [MD:M00007]. Phosphoribosyl pyrophosphate (PRPP) formed from ribose-5P [MD:M00005] is an activated compound used in the biosynthesis of histidine and purine/pyrimidine nucleotides. This pathway map also shows the Entner-Doudoroff pathway where 6-P-gluconate is dehydrated and then cleaved into pyruvate and glyceraldehyde-3P [MD:M00008].
No. of Genes in ADHDgene  4
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 4)

Literature-origin genes (count: 0)

Genes from other sources Help(count: 4)

Approved Symbol Approved Name Location Source
FBP2 fructose-1,6-bisphosphatase 2 9q22.3 Mapped by significant region
FBP1 fructose-1,6-bisphosphatase 1 9q22.3 Mapped by significant region
ALDOA aldolase A, fructose-bisphosphate 16p11.2 Mapped by CNV
ALDOB aldolase B, fructose-bisphosphate 9q21.3-q22.2 Mapped by significant region