ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Other Variant Report

Basic Info
Name TH_intron1_(TCAT)n
Type microsatellite
Location intron 1
Length of Repeat Unit 4bp
Related Gene TH
No. of Study 5 (significant: 0; non-significant 5; trend: 0)

Variant related studies (count: 5)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Hawi Z, 2005 TDT P-value=0.16, X2=2.5, OR=1.8 for paternel tra...... TDT P-value=0.16, X2=2.5, OR=1.8 for paternel transmission; TDT P-value=0.24, X2=1.7, OR=1.5 for maternal transmission More... a trend was seen for paternal transmission and no significan...... a trend was seen for paternal transmission and no significant association was observed for maternal transmission More... Non-significant
Comings DE, 1995 P-value>0.05, X2=3.30 P-value>0.05, X2=3.30 All patient groups showed no significant differences in the ...... All patient groups showed no significant differences in the distribution of the five repeat-size alleles compared to controls. More... Non-significant
Payton A, 2001 allelic TDT P-value=0.96 allelic TDT P-value=0.96 there was no evidence of preferential transmission of any ma...... there was no evidence of preferential transmission of any marker allele More... Non-significant
Barr CL, 2000 (b) 179-198bp TDT smallest P-value=0.479 for allele 191bp TDT smallest P-value=0.479 for allele 191bp no significant difference in the transmission of any of the ...... no significant difference in the transmission of any of the alleles More... Non-significant
Kirley A, 2002 HHRR: P-value=0.34 (RR=1.1, OR=1.21); TDT: P-value=0.331 (OR...... HHRR: P-value=0.34 (RR=1.1, OR=1.21); TDT: P-value=0.331 (OR=1.36); TDT by presence of family history: P-value=0.27 (OR[95%CI]=3[0.68-13.31]); TDT of Paternal and Maternal transmissions: P-value=0.015 (OR[95%CI]=4.29[1.32-13.88]). More... no significant differences between transmitted and non-trans...... no significant differences between transmitted and non-transmitted alleles More... Non-significant