ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Other Variant Report

Basic Info

Name	TH_intron1_(TCAT)n
Type	microsatellite
Location	intron 1
Length of Repeat Unit	4bp
Related Gene	TH
No. of Study	5 (significant: 0; non-significant 5; trend: 0)

Variant related studies (count: 5)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Barr CL, 2000 (b)	179-198bp		TDT smallest P-value=0.479 for allele 191bp TDT smallest P-value=0.479 for allele 191bp	no significant difference in the transmission of any of the ...... no significant difference in the transmission of any of the alleles More...	Non-significant
Comings DE, 1995			P-value>0.05, X²=3.30 P-value>0.05, X²=3.30	All patient groups showed no significant differences in the ...... All patient groups showed no significant differences in the distribution of the five repeat-size alleles compared to controls. More...	Non-significant
Kirley A, 2002			HHRR: P-value=0.34 (RR=1.1, OR=1.21); TDT: P-value=0.331 (OR...... HHRR: P-value=0.34 (RR=1.1, OR=1.21); TDT: P-value=0.331 (OR=1.36); TDT by presence of family history: P-value=0.27 (OR[95%CI]=3[0.68-13.31]); TDT of Paternal and Maternal transmissions: P-value=0.015 (OR[95%CI]=4.29[1.32-13.88]). More...	no significant differences between transmitted and non-trans...... no significant differences between transmitted and non-transmitted alleles More...	Non-significant
Payton A, 2001			allelic TDT P-value=0.96 allelic TDT P-value=0.96	there was no evidence of preferential transmission of any ma...... there was no evidence of preferential transmission of any marker allele More...	Non-significant
Hawi Z, 2005			TDT P-value=0.16, X²=2.5, OR=1.8 for paternel tra...... TDT P-value=0.16, X²=2.5, OR=1.8 for paternel transmission; TDT P-value=0.24, X²=1.7, OR=1.5 for maternal transmission More...	a trend was seen for paternal transmission and no significan...... a trend was seen for paternal transmission and no significant association was observed for maternal transmission More...	Non-significant