ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Other Variant Report

Basic Info

Name	MAOA_exon8_941G/T
Type	point mutation
Location	exon 8
Related Gene	MAOA
No. of Study	3 (significant: 2; non-significant 1; trend: 0)

Variant related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Xu X, 2007(a)	G/T		Single marker TDT P-value=0.034; sex specific analysis: P-va...... Single marker TDT P-value=0.034; sex specific analysis: P-value=0.04 in male, P-value=0.56 in female More...	TDT analysis showed a significant increase in transmission o...... TDT analysis showed a significant increase in transmission of the G-allele of 941G/T More...	Significant
Lawson DC, 2003	G/T		allelic TDT P-value=0.80, X²(1df)=0.06 in full sa...... allelic TDT P-value=0.80, X²(1df)=0.06 in full sample, allelic TDT P-value=0.90, X²(1df)=0.02 in male probands; OR(total sample)=0.99, OR(male probands)=1.23 in case-control analysis More...	there was no evidence of association with ADHD using case co...... there was no evidence of association with ADHD using case control analysis; no preferential transmission of alleles was found in the total sample or in the male probands only More...	Non-significant
Domschke K, 2005	T/G		allelic TDT P-value=0.03, X²=5.1, df=1; TDT P-val...... allelic TDT P-value=0.03, X²=5.1, df=1; TDT P-value=0.06, X²=4.3 in the sample for parental history of ADHD More...	showed significantly higher transmission of the more active ...... showed significantly higher transmission of the more active 941G allele to ADHD cases More...	Significant