ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Other Variant Report

Basic Info
Name HLA-DRB1_alleles01-10
Type HLA-DRB1 alleles
Related Gene HLA-DRB1
No. of Study 2 (significant: 1; non-significant 1; trend: 0)

Variant related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Payton A, 2003 allele 1-10 allelic TDT simulated global P-value=0.16, X2=10....... allelic TDT simulated global P-value=0.16, X2=10.7 for the full sample, allelic TDT simulated global P-value=0.13, X2=11.31 for the complete trios; allelic TDT simulated global P-value=0.86, X2=0.03 for DRB*01, allelic TDT simulated global P-value=0.25, X2=1.22 for DRB*04 in the full sample; OR=1.1 for DRB*01, OR=1.0 for DRB*04 in the case-control analysis More... no preferential transmission of any allele was noted and the...... no preferential transmission of any allele was noted and the case-control findings were also negative More... Non-significant
Aureli A, 2008 allele 1-10 Fisher exact probability test P-value=0.45, OR=0.61 for DRB1...... Fisher exact probability test P-value=0.45, OR=0.61 for DRB1*01, Fisher exact probability test P-value=0.34, OR=1.59 for DRB1*02, Fisher exact probability test P-value=0.81, OR=0.84 for DRB1*03, Fisher exact probability test P-value=0.001, corrected P-value=0.01, OR=4.81 for DRB1*04, Fisher exact probability test P-value=0.03, OR=0.51 for DRB1*05, Fisher exact probability test P-value=0.71, OR=0.85 for DRB1*06, Fisher exact probability test P-value=0.28, OR=1.57 for DRB1*07, Fisher exact probability test P-value=0.70, OR=1.36 for DRB1*08 More... HLA-DR4 frequencies of the ADHD group were significantly dif...... HLA-DR4 frequencies of the ADHD group were significantly different from controls, and frequencies of other HLA-DRB1 alleles did not differ significantly More... Significant