Reference |
Allele Change |
Risk Allele |
Statistical Values |
Author Comments |
Result of Statistical Analysis |
Bhaduri N, 2005 |
C/T |
|
allelic HHRR P-value=0.7082, X2(df=1)=0.14, RR=0.......
allelic HHRR P-value=0.7082, X2(df=1)=0.14, RR=0.93
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|
suggested lack of significant association between transmissi......
suggested lack of significant association between transmission of this polymorphism and ADHD
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|
Non-significant
|
Wigg K, 2002 |
C/T |
T |
TDT allele test P-value=0.07 (one-sided)
TDT allele test P-value=0.07 (one-sided)
|
no significant evidence for biased transmission
no significant evidence for biased transmission
|
Non-significant
|
Roman T, 2002 |
C/T |
|
HRR analysis: P-value=0.03 for whole sample of ADHD probands......
HRR analysis: P-value=0.03 for whole sample of ADHD probands, P-value=0.42 for families with ADHD parental diagnosis (FH+), P-value=0.01 for families with no familial history of ADHD (FH-)
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|
The A2 allele was significantly more transmitted than not tr......
The A2 allele was significantly more transmitted than not transmitted
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|
Significant
|
Payton A, 2001 |
G/T |
|
allelic TDT P-value=0.49
allelic TDT P-value=0.49
|
there was no evidence of preferential transmission of any ma......
there was no evidence of preferential transmission of any marker allele
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|
Non-significant
|
Inkster B, 2004 |
C/T |
2 allele |
TDT P-value=0.31, X2=1.03, df=1; TDT P-value=0.12......
TDT P-value=0.31, X2=1.03, df=1; TDT P-value=0.12, X2=2.37, df=1 of males; TDT P-value=0.37, X2=0.82, df=1 of females, for 2 allele in the family-based sample. TDT P-value=0.057, X2=3.63, df=1 for 2 allele in the case-control sample
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|
the TDT analysis showed weak over-transmission of the DBH Ta......
the TDT analysis showed weak over-transmission of the DBH TaqI 2 allele in both samples; the family-based analysis stratified by proband gender revealed that only males were contributing to the biased transmission observed; no gender-specific effects for the case-control sample were observed
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|
Non-significant
|
Smith KM, 2003 |
Allele 1: no site; Allele 2: TaqI recognition site |
A1 |
Genotypic chi-square P-value=0.064, Allelic chi-square P-val......
Genotypic chi-square P-value=0.064, Allelic chi-square P-value=0.018; OR=1.96, RR=1.33
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|
A1 allele was observed more frequently in the ADHD compared ......
A1 allele was observed more frequently in the ADHD compared to the control group; DBH TaqI A polymorphism is significantly associated with ADHD
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|
Significant
|
Hawi Z, 2003 |
C/T |
|
HHRR P-value=0.0027, X2=9, RR=1.38 for allele1
HHRR P-value=0.0027, X2=9, RR=1.38 for allele1
|
showed highly significant association with ADHD
showed highly significant association with ADHD
|
Significant
|
Kirley A, 2002 |
C/T |
|
HHRR: P-value=0.0027 (RR=1.38, OR=1.87); TDT: P-value=0.01 (......
HHRR: P-value=0.0027 (RR=1.38, OR=1.87); TDT: P-value=0.01 (OR=1.88); TDT by presence of family history: P-value=0.307 (OR[95%CI]=2.44[0.59-10.04]); TDT of Paternal and Maternal transmissions: P-value=0.98 (OR[95%CI]=1.01[0.36-2.90])
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|
Significant preferential transmission
Significant preferential transmission
|
Significant
|