ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Other Variant Report

Basic Info
Name DBH_5'-flanking_(GT)n
Type microsatellite
Location 5' flanking, approximately 4.7 kb 5' to the transcriptional start site
Related Gene DBH
No. of Study 5 (significant: 0; non-significant 5; trend: 0)

Variant related studies (count: 5)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Wigg K, 2002 A3, A4 A4 TDT P-value=0.59 TDT P-value=0.59 no significant evidence for biased transmission no significant evidence for biased transmission Non-significant
Hawi Z, 2003 Global X2=0.98; X2=0, RR=1 for allele1...... Global X2=0.98; X2=0, RR=1 for allele1; HHRR P-value=0.73, X2=0.1, RR=0.94 for allele2; HHRR P-value=0.69, X2=0.16, RR=1.04 for allele3; HHRR P-value=0.8, X2=0.06, RR=0.97 for allele4; HHRR P-value=0.99, RR=1 for allele5 More... no significant transmission of any allele to ADHD was report...... no significant transmission of any allele to ADHD was reported More... Non-significant
Smith KM, 2003 Alleles A1, A2, A3, A4, A6 Genotype groupings chi-square P-value=0.28, Allele groupings...... Genotype groupings chi-square P-value=0.28, Allele groupings chi-square P-value=0.269 More... the A4 allele and genotypes occurred more frequently in the ...... the A4 allele and genotypes occurred more frequently in the ADHD group compared to controls, although these differences did not reach statistical significance More... Non-significant
Bhaduri N, 2010 12R, 13R, 14R allelic frequencies P-value=0.08, X2=4.85; genoty...... allelic frequencies P-value=0.08, X2=4.85; genotypic frequencies P-value=0.92, X2=0.91; HHRR P-value=0.68, OR=1.18, X2=0.17, TDT P-value=0.69, RR=1.67, X2=0.2 for 14R allele; HHRR P-value=0.35, OR=0.80, X2=0.88, TDT P-value=0.31, RR=0.77, X2=1.03 for 13R allele, HHRR P-value=0.5, OR=1.17, X2=0.5, TDT P-value=0.45, RR=1.21, X2=0.56 for 12R allele for overall transmission; HHRR P-value=0.7, OR=1.37, X2=0.15, TDT P-value=0.71, RR=1.33, X2=0.14 for 14R allele; HHRR P-value=0.13, OR=0.64, X2=2.24, TDT P-value=0.09, RR=0.53, X2=2.84 for 13R allele, HHRR P-value=0.19, OR=1.53, X2=1.7, TDT P-value=0.13, RR=1.8, X2=2.32 for 12R allele for paternal transmission; HHRR P-value=0.81, OR=1.13, X2=0.06, TDT P-value=0.81, RR=1.11, X2=0.05 for 14R allele; HHRR P-value=0.87, OR=1.06, X2=0.03, TDT P-value=0.86, RR=1.06, X2=0.03 for 13R allele, HHRR P-value=0.75, OR=0.9, X2=0.1, TDT P-value=0.74, RR=0.89, X2=0.11 for 12R allele for paternal transmission More... no significant association with ADHD no significant association with ADHD Non-significant
Nyman ES, 2007 No available information. No available information. No evidence of association was seen. No evidence of association was seen. Non-significant