ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Other Variant Report

Basic Info

Name	BDNF_C270T
Type	point mutation
Location	5' UTR
Related Gene	BDNF
No. of Study	3 (significant: 2; non-significant 1; trend: 0)

Variant related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Xu X, 2007(b)	C/T		UK sample: TDT P-value=0.176, HHRR P-value=0.180, TRANSMIT P...... UK sample: TDT P-value=0.176, HHRR P-value=0.180, TRANSMIT P-value=0.686; Taiwanese sample: TDT P-value=0.009, HHRR P-value=0.008, TRANSMIT P-value=0.008; Combined sample: TDT P-value=0.007, HHRR P-value=0.007, TRANSMIT P-value=0.037 More...	there was evidence of increased transmission of the C allele...... there was evidence of increased transmission of the C allele in the Taiwanese sample and combined sample. More...	Significant
Aureli A, 2010	C/T		Fisher's exact test P-value=0.02, X²=5.2, OR=3.86...... Fisher's exact test P-value=0.02, X²=5.2, OR=3.86 for C allele, Pearson's chi-squared test P-value=0.001, X²=11.96, OR=16.3 for the C/C genotype More...	both C allele and the C/C genotype was more frequent in both...... both C allele and the C/C genotype was more frequent in both ADHD and ID groups compared with the controls More...	Significant
Friedel S, 2005	C/T		genotypic Cochran-Armitage trend test P-value>0.2 genotypic Cochran-Armitage trend test P-value>0.2	no significant difference was observed no significant difference was observed	Non-significant