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- Data Summary
GO Report
Basic Info
| ID | GO:0005230 |
|---|---|
| Name | extracellular ligand-gated ion channel activity |
| Type | Molecular Function |
| No. of Genes in ADHDgene | 7 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 7)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| GABRG1 | gamma-aminobutyric acid (GABA) A receptor, gamma 1 | 4p12 | 1(0/0/1) | |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A | 11q23.1-q23.2 | 1(0/1/0) |
Genes from other sources (count: 5)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | Mapped by CNV; Mapped by significant region | |
| CHRFAM7A | CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion | Mapped by significant region | |
| GABRG3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 | Mapped by CNV; Mapped by significant region | |
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 | Mapped by CNV; Mapped by significant region | |
| STX1B | syntaxin 1B | Mapped by CNV | TAS[8105537] |