ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005230
Name extracellular ligand-gated ion channel activity
Type molecular function
No. of Genes in ADHDgene  7
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 7)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 4p12 1(0/0/1) IEA
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 11q23.1-q23.2 1(0/1/0) NAS

Genes from other sources Help (count: 5)

Approved Symbol Approved Name Source Evidence[PMID]
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 Mapped by CNV; Mapped by significant region NAS
STX1B syntaxin 1B Mapped by CNV TAS[8105537]
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion Mapped by significant region IEA
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Mapped by CNV; Mapped by significant region IEA
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 Mapped by CNV; Mapped by significant region IEA