ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PIGW
Symbol Alias	Gwt1, FLJ37433
Approved Name	phosphatidylinositol glycan anchor biosynthesis, class W
Previous Name	"phosphatidylinositol glycan, class W"
Location	17q21.1
Position	chr17:34890847-34895159, 1
External Links	HGNC: 23213 Entrez Gene: 284098 Ensembl: ENSG00000184886 UCSC: uc002hmz.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 2)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_191	chr17:31889664-33323543 (NCBI Build 35 (hg17))	1774728	17q12	Deletion (hemizygous)	Paternal
CNV_Williams[2010]_7	chr17:31964475-33297438 (NCBI Build 36.1 (hg18))	1278621	17q12	Gain	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043687	post-translational protein modification	biological process	TAS	42
GO:0044267	cellular protein metabolic process	biological process	TAS	78
GO:0006501	C-terminal protein lipidation	biological process	TAS	4
GO:0005789	endoplasmic reticulum membrane	cellular component	TAS	159
GO:0016021	integral to membrane	cellular component	IEA	932
GO:0016254	preassembly of GPI anchor in ER membrane	biological process	TAS	4
GO:0016746	transferase activity, transferring acyl groups	molecular function	IEA	12

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	5

Genes shared at least 5 GO terms with PIGW (count: 3)

Gene Symbol	Pathway Count	Pathway List
PIGL	6	post-translational protein modification; cellular protein metabolic process; C-terminal protein lipidation; endoplasmic reticulum membrane; integral to membrane; preassembly of GPI anchor in ER membrane;
PIGB	6	post-translational protein modification; cellular protein metabolic process; C-terminal protein lipidation; endoplasmic reticulum membrane; integral to membrane; preassembly of GPI anchor in ER membrane;
PIGQ	6	post-translational protein modification; cellular protein metabolic process; C-terminal protein lipidation; endoplasmic reticulum membrane; integral to membrane; preassembly of GPI anchor in ER membrane;

Genes shared at least 2 KEGG pathways with PIGW (count: 0)

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Region: chr17:34890847..34895159 View in gBrowse