ADHDgene Database

Gene Report

Basic Info

Approved Symbol	KCNC1
Symbol Alias	Kv3.1
Approved Name	potassium voltage-gated channel, Shaw-related subfamily, member 1
Location	11p15
Position	chr11:17756359-17804602, +
External Links	HGNC: 6233 Entrez Gene: 3746 Ensembl: ENSG00000129159 UCSC: uc009yhc.1
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Lesch KP, 2008	No significant or Trend associated SNP was mapped in this gene.	Non-significant

Gene related SNPs (count: 10)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs3893215	Chr11:17764830(Fwd)	intron_variant	1(0/1/0)

rs_ID	Location	Functional Annotation
rs16934680	Chr11:17764913(Fwd)	intron_variant
rs10766435	Chr11:17786709(Fwd)	intron_variant
rs7926535	Chr11:17788400(Fwd)	intron_variant
rs10444224	Chr11:17789634(Fwd)	intron_variant
rs917032	Chr11:17790227(Fwd)	intron_variant; upstream_gene_variant
rs6486396	Chr11:17770726(Fwd)	intron_variant
rs7110441	Chr11:17770833(Fwd)	intron_variant
rs7124411	Chr11:17771168(Fwd)	intron_variant
rs757512	Chr11:17774035(Fwd)	intron_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005251	delayed rectifier potassium channel activity	Molecular Function		3
GO:0005886	plasma membrane	Cellular Component		772
GO:0005249	voltage-gated potassium channel activity	Molecular Function	TAS[8449507]	3
GO:0008076	voltage-gated potassium channel complex	Cellular Component		6
GO:0051260	protein homooligomerization	Biological Process		34
GO:0006813	potassium ion transport	Biological Process	TAS[8449507]	11
GO:0007268	synaptic transmission	Biological Process		96

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with KCNC1 (count: 2)

Gene Symbol	Pathway Count	Pathway List
KCNF1	6	delayed rectifier potassium channel activity; plasma membrane; voltage-gated potassium channel complex; protein homooligomerization; potassium ion transport; synaptic transmission;
KCNG4	5	delayed rectifier potassium channel activity; plasma membrane; voltage-gated potassium channel complex; protein homooligomerization; synaptic transmission;

Genes shared at least 2 KEGG pathways with KCNC1 (count: 0)

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Region: chr11:17756359..17804602 View in gBrowse