SNP |
Allele Change |
Risk Allele |
Statistical Values |
Author Comments |
Result of Statistical Analysis |
rs4818 |
G/C |
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genotype: (GG vs GC vs CC), chi-square tests, P-value=0.372, X2=4.258; allele: chi-square tests, P-value=0.174, X2=3.494 among the groups |
No significant difference was observed between the groups in......
No significant difference was observed between the groups in terms of allele frequencies for COMT (rs4818).
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Non-significant
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rs2242447 |
C/T |
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genotype: (CC vs CT vs TT), chi-square tests, P-value=0.008, X2=13.888; allele: chi-square tests, P-value=0.013, X2=8.700 among groups; genotypic P-value=0.019, allelic P-value = 0.003, X2=8.694, df=1 between the ADHD and the Non-ADHD groups; Presence of the C allele (CC + CT): P-value=0.014, X2=8.581, df=2, among the groups; X2= 7.125, df = 1, P-value = 0.008 between the ADHD and the Non-ADHD groups; Presence of the T allele (TT + CT): X2=6.229, df=2, P-value = 0.044, correction P-value>0.017 among the groups |
A significant difference was determined between the groups f......
A significant difference was determined between the groups for NET1 (rs2242447). The significant difference for NET1 (rs2242447) was between the ADHD and Non-ADHD groups. The C allele had a higher frequency in the ADHD group, and the T allele in the Non-ADHD group. There were no differences in allele frequencies for NET1 (rs2242447) between the Non-ADHD and HC groups, or the ADHD and HC groups, after the Bonferroni correction. The NET1 (rs2242447) C allele presence was significantly lower in the Non-ADHD group compared to both the ADHD and HC groups. There was no significant difference in terms of allele presence between the ADHD and HC groups after the Bonferroni correction. Nevertheless, while there was a statistically significant difference in the rates of allele presence of the NET1 (rs2242447) T allele in three-group comparison, there was no significant difference in two-group comparisons after the Bonferroni correction.
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Significant
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rs6311 |
A/G |
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genotype: (AA vs AG vs GG ), chi-square tests, P-value=0.117, X2=7.379; allele: chi-square tests, P-value=0.042, X2=6.339 among the groups; allelic P-value = 0.012, X2=6.315, df = 1, between the ADHD and the HC groups; Presence of the A allele (AA + AG): P-value=0.028, X2=7.187, df = 2 among the groups; P-value = 0.007, X2 =7.201, df = 1, between the ADHD and HC groups; Presence of the G allele (GG + AG); X2 =1.813, P-value =0.014 among the groups |
A significant difference was determined between the groups f......
A significant difference was determined between the groups for 5-HT2A (rs6311). 5-HT2A (rs6311) exhibited a significant difference between the ADHD and HC groups. There were no differences in allele frequencies of 5-HT2A (rs6311) between the ADHD and Non-ADHD groups, and the Non-ADHD and HC groups, after the Bonferroni correction. The 5-HT2A (rs6311) G allele exhibited no significant difference among the groups, while A allele presence was significantly higher in the ADHD group than in the HC group. There were no differences in rates of A allele presence between the ADHD and Non-ADHD groups, and the Non-ADHD and HC groups, after the Bonferroni correction.
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Significant
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rs1051312 |
C/T |
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genotype: (CC vs CT vs TT), chi-square tests, P-value=0.279, X2=5.084; allele: chi-square tests, P-value=0.692, X2=0.736 among the groups |
No significant difference was observed between the groups in......
No significant difference was observed between the groups in terms of allele frequencies for SNAP-25 (rs1051312).
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Non-significant
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rs3746544 |
G/T |
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genotype: (GG vs GT vs TT), chi-square tests, P-value=0.003, X2=16.290; allele: chi-square tests, P-value=0.020, X2=7.833 among the groups; genotypic P-value=0.001, X2=13.049, df = 2 between the ADHD and HC groups, P-value=0.017 between the Non-ADHD and HC groups; allelic P-value= 0.009, X2=6.884, df=1 between the ADHD and HC groups; Presence of the G allele (GG + GT): P-value=0.605, X2=1.005, df=2 among the groups; Presence of the T allele (TT + GT): P-value=0.0001, X2=20.845, df=2 among the groups, P-value=0.0001, X2 = 16.206, df = 1 between both the ADHD and HC groups, P-value=0.001, X2 = 10.641, df = 1 between the Non-ADHD and HC groups |
A significant difference was determined between the groups f......
A significant difference was determined between the groups for SNAP-25 (rs3746544). SNAP-25 (rs3746544) exhibited a significant difference between the ADHD and HC groups. T allele frequency was higher in parents with children with ADHD compared with the HC group, while G allele frequency was higher in the HC group. There were no differences in allele frequencies for SNAP-25 (rs3746544) between the ADHD and Non-ADHD groups, or the Non- ADHD and HC groups , after the Bonferroni correction. For SNAP-25 (rs3746544), while the G allele presence exhibited no significant difference among the groups, the presence of the T allele in the ADHD and non-ADHD groups was higher than that in the HC group. In contrast, there was no significant difference in terms of the presence of the G or T alleles between the ADHD and the Non-ADHD groups.
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Significant
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rs6332 |
A/G |
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genotype: (AA vs AG vs GG),chi-square tests, P-value=0.463, X2=3.596; allele: chi-square tests, P-value=0.445, X2=1.621 among the groups |
No significant difference was observed between the groups in......
No significant difference was observed between the groups in terms of allele frequencies for NTF3 (rs6332).
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Non-significant
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