ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs821616 dbSNP Ensembl
Location	chr1:232144598(Fwd)
Variant Alleles	A/T
Ancestral Allele	A
Functional Annotation	3_prime_UTR_variant; missense_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant. Polyphen Annotation: possibly damaging(ENST00000439617; ENST00000366637) \| unknown(ENST00000535983) SIFT Annotation: deleterious(ENST00000439617) \| tolerated(ENST00000366637)
Consequence to Transcript	3_prime_UTR_variant(ENST00000422590; ENST00000537876) missense_variant(ENST00000439617; ENST00000366637; ENST00000535983) nc_transcript_variant(ENST00000427560) NMD_transcript_variant(ENST00000422590) non_coding_exon_variant(ENST00000427560)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Jacobsen, K. K.,2013			chi-square tests P-value=0.58 (OR=1.05;95%CI=0.89-1.24) chi-square tests P-value=0.58 (OR=1.05;95%CI=0.89-1.24)	This SNP was not significant associated with ADHD This SNP was not significant associated with ADHD	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DISC1	disrupted in schizophrenia 1	1q42.1	1(1/0/0)

Genes from other sources (count: 0)

SNPs in LD with rs821616 (count: 38) View in gBrowse (chr1:232094259..232151908 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 38)

rs_ID	Functional Annotation	r²[population]
rs1772703	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.952[CEU]
rs701163	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 0.904[CHB]
rs1772696	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]
rs866055	downstream_gene_variant; intron_variant	0.955[CEU]
rs3121910	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 0.904[CHB]; 0.925[YRI]
rs1754609	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.957[CEU]
rs821622	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.931[YRI]
rs821615	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[YRI]
rs1754605	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 0.904[CHB]; 0.963[YRI]
rs821596	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 0.814[CHB]
rs821628	downstream_gene_variant; intron_variant	1.0[CEU]; 0.911[CHB]; 0.89[YRI]
rs1772701	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.92[YRI]
rs821660	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.957[CEU]; 0.911[CHB]
rs821598	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]
rs2772114	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.957[CEU]
rs1772699	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.923[YRI]
rs1754606	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 0.904[CHB]; 0.963[YRI]
rs2806475	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.957[CEU]
rs821651	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]
rs1772702	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.954[CEU]
rs866596	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.962[YRI]
rs821605	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[YRI]
rs821602	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.957[CEU]; 1.0[CHB]; 1.0[YRI]
rs821653	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.803[YRI]
rs821647	intron_variant	0.834[CHB]
rs821592	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.827[CEU]; 0.911[CHB]
rs821623	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs2772120	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]
rs1754608	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.925[YRI]
rs1754603	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.857[YRI]
rs860272	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[YRI]
rs2806474	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]
rs821652	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]
rs821629	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.857[YRI]
rs821621	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.962[YRI]
rs821620	downstream_gene_variant; intron_variant	0.957[CEU]; 1.0[CHB]; 0.847[JPT]; 0.833[YRI]
rs821661	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]
rs1754604	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]