ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs6675281 dbSNP Ensembl
Location chr1:231954101(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation 3_prime_UTR_variant; 5_prime_UTR_variant; intron_variant; missense_variant; NMD_transcript_variant; synonymous_variant; upstream_gene_variant.
Polyphen Annotation: probably damaging(ENST00000366633; ENST00000366636; ENST00000439617; ENST00000535983; ENST00000602281)
SIFT Annotation: deleterious(ENST00000366633; ENST00000366636; ENST00000439617; ENST00000535983; ENST00000602281)
Consequence to Transcript 3_prime_UTR_variant(ENST00000295051; ENST00000366632; ENST00000422590; ENST00000535944; ENST00000602567; ENST00000602634; ENST00000602700; ENST00000602713; ENST00000602822; ENST00000602873; ENST00000602885; ENST00000602956; ENST00000602962)
5_prime_UTR_variant(ENST00000366637)
intron_variant(ENST00000537876)
missense_variant(ENST00000366633; ENST00000366636; ENST00000439617; ENST00000535983; ENST00000602281)
NMD_transcript_variant(ENST00000295051; ENST00000366632; ENST00000422590; ENST00000535944; ENST00000602567; ENST00000602634; ENST00000602700; ENST00000602713; ENST00000602822; ENST00000602885; ENST00000602956; ENST00000602962)
synonymous_variant(ENST00000539444)
upstream_gene_variant(ENST00000427560)
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Jacobsen, K. K.,2013 chi-square tests P-value=0.18 (OR=1.16;95%CI=0.93-1.44); a p...... chi-square tests P-value=0.18 (OR=1.16;95%CI=0.93-1.44); a positive MDQ-score after adjusting for gender and ADHD-status OR=1.44, 95%CI=1.08-1.93,P-value=0.01 More... This SNP showed a nominally signi?cant association between r...... This SNP showed a nominally signi?cant association between rs6675281 and a positive MDQ-score after adjusting for gender and ADHD-status . More... Significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 1)


SNPs in LD with rs6675281 (count: 5) View in gBrowse (chr1:231953994..231972811 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 5)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014