ADHDgene Database

SNP Report

Basic Info

Name	rs3779312 dbSNP Ensembl
Location	Chr7:77711756(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000419488; ENST00000354212; ENST00000522391; ENST00000519748) nc_transcript_variant(ENST00000519748)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Stergiakouli E., 2012	T/C	T	P=0.00000838, OR=1.37, 95% CI=1.19-1.57 P=0.00000838, OR=1.37, 95% CI=1.19-1.57	One of the top 23 independent SNP in this ADHD GWAS. One of the top 23 independent SNP in this ADHD GWAS.	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	7q21	1(0/0/1)

SNPs in LD with rs3779312 (count: 9) View in gBrowse (chr7:77707557..77738994 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs4590377	downstream_gene_variant; intron_variant	0.834[CHD]; 0.842[JPT]
rs10229186	intron_variant; nc_transcript_variant	0.827[CEU]; 0.834[CHB]; 1.0[JPT]
rs7807726	intron_variant; nc_transcript_variant	0.926[CEU]; 1.0[CHB]; 0.909[JPT]; 0.824[YRI]
rs3779308	intron_variant; nc_transcript_variant	0.941[CEU]; 0.916[CHB]; 1.0[JPT]
rs3779310	intron_variant; nc_transcript_variant	0.873[CEU]; 0.904[CHB]; 0.91[JPT]
rs3779309	intron_variant; nc_transcript_variant	0.935[CEU]; 0.904[CHB]; 1.0[JPT]
rs17593991	intron_variant; nc_transcript_variant	0.827[CEU]; 0.904[JPT]
rs11761568	intron_variant; nc_transcript_variant	0.877[CEU]; 0.916[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.878[TSI]
rs3807747	intron_variant; nc_transcript_variant	0.941[CEU]; 0.916[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.932[MEX]; 0.96[TSI]