ADHDgene Database

SNP Report

Basic Info

Name	rs2381164 dbSNP Ensembl
Location	Chr9:34553968(Fwd)
Variant Alleles	G/C
Ancestral Allele	G
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000417345) intron_variant(ENST00000378980; ENST00000351266)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases M, 2008			genotypic P-value=0.03; genotypic P-value=0.083 in dominant ...... genotypic P-value=0.03; genotypic P-value=0.083 in dominant model; genotypic P-value=0.015, OR=1.69 (1.11-2.56) in recessive model; allelic P-value=0.015, OR=1.28 (1.05-1.59) in Children More...	provided evidence of association with childhood ADHD provided evidence of association with childhood ADHD	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
CNTFR	ciliary neurotrophic factor receptor	9p13	1(1/0/0)

SNPs in LD with rs2381164 (count: 7) View in gBrowse (chr9:34550295..34572767 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs4472605	intron_variant; upstream_gene_variant	0.823[JPT]
rs10758268	downstream_gene_variant; intron_variant; nc_transcript_variant	0.883[CEU]; 0.818[CHB]; 0.953[JPT]
rs4363285	downstream_gene_variant; intron_variant	0.868[CHB]; 0.82[JPT]
rs10814119	downstream_gene_variant; upstream_gene_variant	1.0[CHB]; 0.953[JPT]
rs10758267	intron_variant; upstream_gene_variant	0.842[CEU]; 0.866[JPT]
rs2274592	downstream_gene_variant; intron_variant	1.0[CHB]; 1.0[JPT]
rs10738931	intron_variant; upstream_gene_variant	0.815[JPT]