ADHDgene Database

SNP Report

Basic Info

Name	rs2126953 dbSNP Ensembl
Location	chr5:52161157(Fwd)
Variant Alleles	T/G
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000282588; ENST00000509049; ENST00000513737; ENST00000514262) nc_transcript_variant(ENST00000509049; ENST00000513737; ENST00000514262)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Laurin N, 2008(a)	T/G		P-value=0.078 in the catergorical analysis, P-value>0.05 in ...... P-value=0.078 in the catergorical analysis, P-value>0.05 in the quantitative analysis More...	no significant evidence of association no significant evidence of association	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ITGA1	integrin, alpha 1	5q11.1	2(0/2/0)

SNPs in LD with rs2126953 (count: 4) View in gBrowse (chr5:52157374..52163400 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs2169782	intron_variant; upstream_gene_variant	0.847[CEU]; 0.898[TSI]; 0.947[CHB]; 1.0[JPT]; 0.916[GIH]; 0.834[MKK]
rs2447867	synonymous_variant; upstream_gene_variant	0.948[CEU]; 1.0[TSI]; 0.827[ASW]; 1.0[CHB]; 1.0[JPT]; 0.958[GIH]; 0.881[MKK]
rs2456222	downstream_gene_variant; intron_variant; nc_transcript_variant	0.895[CEU]; 0.863[TSI]; 0.849[CHB]; 0.861[JPT]
rs2456221	downstream_gene_variant; intron_variant; nc_transcript_variant	0.895[CEU]; 1.0[TSI]; 0.948[CHB]; 1.0[JPT]; 0.835[GIH]