ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs12646862 dbSNP Ensembl
Location	Chr4:21922119(Fwd)
Variant Alleles	A/C
Ancestral Allele	A
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000515786) intron_variant(ENST00000447367; ENST00000382152; ENST00000515786)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Weissflog L., 2012		C	case-control test in aADHD sample: P=0.0147, OR=1.27, 95%CI=...... case-control test in aADHD sample: P=0.0147, OR=1.27, 95%CI=1.0481-1.5371 More...	Nominally significant association findings for KCNIP9 with a...... Nominally significant association findings for KCNIP9 with adult ADHD. More...	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
KCNIP4	Kv channel interacting protein 4	4p15.32	1(1/0/0)

Genes from other sources (count: 0)

SNPs in LD with rs12646862 (count: 25) View in gBrowse (chr4:21911866..21973739 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 1)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs7356396	NMD_transcript_variant; intron_variant	1(1/0/0)	1.0[ASW]; 1.0[CEU]; 0.954[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 0.875[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]

LD-proxies (count: 24)

rs_ID	Functional Annotation	r²[population]
rs12507277	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs9995524	NMD_transcript_variant; intron_variant	0.885[ASW]; 1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 0.847[LWK]; 0.875[MEX]; 0.943[MKK]; 1.0[TSI]
rs11944614	NMD_transcript_variant; intron_variant	0.885[ASW]; 1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 0.847[LWK]; 0.875[MEX]; 0.943[MKK]; 1.0[TSI]
rs10938868	NMD_transcript_variant; intron_variant	0.926[CEU]; 1.0[CHB]; 1.0[JPT]
rs2874977	NMD_transcript_variant; intron_variant	0.815[JPT]
rs10938866	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 0.875[MEX]; 0.963[MKK]; 1.0[TSI]; 1.0[YRI]
rs727633	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 0.875[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs16872134	NMD_transcript_variant; intron_variant	0.926[CEU]; 0.954[CHB]; 1.0[JPT]
rs1849542	intron_variant; nc_transcript_variant	0.855[JPT]
rs10938869	NMD_transcript_variant; intron_variant	0.926[CEU]; 0.954[CHB]; 1.0[JPT]; 1.0[YRI]
rs10029403	NMD_transcript_variant; intron_variant	0.868[CEU]; 0.954[CHB]; 1.0[JPT]
rs10017055	NMD_transcript_variant; intron_variant	0.86[CEU]; 0.85[CHB]; 0.947[JPT]
rs10938872	intron_variant; nc_transcript_variant	0.859[JPT]
rs1398838	NMD_transcript_variant; intron_variant	1.0[CEU]; 0.909[CHB]; 1.0[JPT]
rs13102882	NMD_transcript_variant; intron_variant	0.922[CEU]; 1.0[JPT]
rs9997450	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs10516405	intron_variant; nc_transcript_variant	0.859[JPT]
rs12644787	intron_variant; nc_transcript_variant	0.826[CHB]
rs13126050	NMD_transcript_variant; intron_variant	0.868[CEU]; 0.951[CHB]; 1.0[JPT]
rs2007195	intron_variant; nc_transcript_variant	0.826[CHB]; 0.808[GIH]
rs6821401	NMD_transcript_variant; intron_variant	0.885[ASW]; 1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 0.847[LWK]; 0.875[MEX]; 0.924[MKK]; 1.0[TSI]
rs10516404	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs13109656	NMD_transcript_variant; intron_variant	0.93[CEU]; 0.954[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 0.847[LWK]; 0.875[MEX]; 0.943[MKK]; 0.967[TSI]
rs10026649	NMD_transcript_variant; intron_variant	0.926[CEU]; 0.907[CHB]; 1.0[JPT]