ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Region Report

Basic Info

Region Name	16p13
Chromosome Position	chr16:0-16800000
#studies (significant/non-significant/trend)	3(2/1/0)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result of Statistical Analysis
Smalley SL, 2002	D16S3114, D16S3047, D16S3075, rs1127293, D16S3060	maximum LOD score 4.22 (P=0.0000052) maximum LOD score 4.22 (P=0.0000052)	significant linkage significant linkage	Significant
Ogdie MN, 2003	D16S3114	Multipoint MLS Linkage Analysis: with marker D16S3060, MLS=3...... Multipoint MLS Linkage Analysis: with marker D16S3060, MLS=3.13 (P=0.00007) for wave 1, MLS=0.5 (P=0.06458) for wave 2, MLS=3.73 (P=0.00002) for combined; Single-Point MLS Linkage Analysis: with marker D16S3114, MLS=1.942 (P=0.00139) for wave 1, MLS=0.043 (P=0.32778) for wave 2, MLS=1.738 (P=0.00233) for combined; with marker D16S3047, MLS=1.741 (P=0.00232) for wave 1, MLS=0.257 (P=0.13831) for wave 2, MLS=1.501 (P=0.00427) for combined; with marker rs153783, MLS=0.645 (P=0.04231) for wave 1, MLS=1.409 (P=0.00543) for wave 2, MLS=2.436 (P=0.0004) for combined; with marker rs127293, MLS=1.014 (P=0.01536) for wave 1, MLS=0.253 (P=0.14016) for wave 2, MLS=1.555 (P=0.00373) for combined; with marker D16S3060, MLS=1.268 (P=0.00784) for wave 1, MLS=0.053 (P=0.31297) for wave 2, MLS=1.421 (P=0.00526) for combined More...	significant linkage significant linkage	Significant
Fisher SE, 2002	D16S3075	MLS peak multipoint LOD=0.75 under narrow scheme, MLS peak m...... MLS peak multipoint LOD=0.75 under narrow scheme, MLS peak multipoint LOD=1.51 under broad scheme More...	modest effect (LOD>1.5) was found, but didn't exceed genome-...... modest effect (LOD>1.5) was found, but didn't exceed genome-wide significance thresholds More...	Non-significant

Region related genes (count: 0)

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Region: chr16:0..16800000 View in gBrowse