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- Data Summary
KEGG Pathway Report
Basic Info
| ID | hsa05150 |
|---|---|
| Name | Staphylococcus aureus infection |
| Description | Staphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the effectiveness of the immune system: secreting immune modulating proteins that inhibit complement activation and neutrophil chemotaxis or lysis, modulating the sensitivity to cationic antimicrobial peptides (such as defensin) by increasing the positive net charge of its cytoplasmic membrane, and expression of superantigens that prevent development of a normal immune response or cause an emetic response when ingested. |
| No. of Genes in ADHDgene | 11 |
| Source | Pathway by Database Search |
Pathway related genes in ADHDgene (count: 11)
Literature-origin genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
|---|---|---|---|
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 6p21.3 | 2(1/1/0) |
Genes from other sources (count: 10)
| Approved Symbol | Approved Name | Location | Source |
|---|---|---|---|
| C3AR1 | complement component 3a receptor 1 | 12p13.31 | Mapped by PBA pathway |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 16p13.1-p11 | Mapped by CNV |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 1q23 | Mapped by CNV |
| FCGR3A | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) | 1q23 | Mapped by CNV |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 1q23 | Mapped by CNV |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 1q23 | Mapped by CNV |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 1q23 | Mapped by CNV |
| C5 | complement component 5 | 9q33-q34 | Mapped by significant region |
| MASP2 | mannan-binding lectin serine peptidase 2 | 1p36.3-p36.2 | Mapped by literature SNP |
| DSG1 | desmoglein 1 | 18q12.1 | Mapped by significant region |