ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Other Variant Report

Basic Info
Name DRD4_promoter_-521C/T
Type point mutation
Location promoter
Related Gene DRD4
No. of Study 6 (significant: 0; non-significant 6; trend: 0)

Variant related studies (count: 6)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Barr CL, 2001(d) C/T allelic P-value=0.366, X2=0.818 allelic P-value=0.366, X2=0.818 there was no evidence for biased transmission of the alleles there was no evidence for biased transmission of the alleles Non-significant
Mill J, 2003 C/T TRANSMIT P-value>0.05 TRANSMIT P-value>0.05 no evidence of biased transmission to ADHD probands was foun...... no evidence of biased transmission to ADHD probands was found More... Non-significant
Lowe N, 2004 (a) G/A TDT P-value=0.166, OR=1.25, 95% CI=0.96-1.77 TDT P-value=0.166, OR=1.25, 95% CI=0.96-1.77 insignificant excess of allele A insignificant excess of allele A Non-significant
Kereszturi E, 2007 C/T No association was found between ADHD and this SNP No association was found between ADHD and this SNP Non-significant
Kirley A, 2004 allelic TDT P-value=0.33, X2=1.13 in combined sub...... allelic TDT P-value=0.33, X2=1.13 in combined subtype More... there was no association between this variant and DSM-IV com...... there was no association between this variant and DSM-IV combined type ADHD More... Non-significant
Payton A, 2001 C/T allelic TDT P-value=0.75 allelic TDT P-value=0.75 there was no evidence of preferential transmission of any ma...... there was no evidence of preferential transmission of any marker allele More... Non-significant