ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SPAM1
Symbol Alias	HYAL5, PH-20, SPAG15
Approved Name	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
Location	7q31
Position	chr7:123565286-123611468, +
External Links	HGNC: 11217 Entrez Gene: 6677 Ensembl: ENSG00000106304 UCSC: uc003vle.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_3	chr7:122788319-123645842 (NCBI Build 36.1 (hg18))	807966	7q31.32-7q31.33	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007342	fusion of sperm to egg plasma membrane	Biological Process		3
GO:0031225	anchored to membrane	Cellular Component		29
GO:0004415	hyalurononglucosaminidase activity	Molecular Function		2
GO:0007155	cell adhesion	Biological Process		86
GO:0005886	plasma membrane	Cellular Component		772
GO:0007339	binding of sperm to zona pellucida	Biological Process	TAS[8195297]	3
GO:0005975	carbohydrate metabolic process	Biological Process		50

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00531	Glycosaminoglycan degradation	3

Genes shared at least 5 GO terms with SPAM1 (count: 0)

Genes shared at least 2 KEGG pathways with SPAM1 (count: 2)

Gene Symbol	Pathway Count	Pathway List
GALNS	2	Metabolic pathways; Glycosaminoglycan degradation;
HYAL4	2	Metabolic pathways; Glycosaminoglycan degradation;

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Region: chr7:123565286..123611468 View in gBrowse