ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SLC38A1
Symbol Alias	ATA1, NAT2, SAT1
Approved Name	solute carrier family 38, member 1
Location	12q13.11
Position	chr12:46576846-46663800, -1
External Links	HGNC: 13447 Entrez Gene: 81539 Ensembl: ENSG00000111371 UCSC: uc001rpc.3
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin; Mapped by Literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Yang L, 2013	Gene with smallest SNP P-value=0.0000746, no significant or Trend associated SNP was mapped in this gene.	Non-significant

Gene related SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs17096738	chr12:46579641(Fwd)	3_prime_UTR_variant; downstream_gene_variant	1(0/1/0)
rs722970	chr7:85803265(Fwd)		1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006811	ion transport	biological process	TAS	32
GO:0001504	neurotransmitter uptake	biological process	TAS	4
GO:0015175	neutral amino acid transmembrane transporter activity	molecular function	NAS[10891391]	6
GO:0006865	amino acid transport	biological process	TAS	8
GO:0016021	integral to membrane	cellular component	NAS[10891391]	932
GO:0005283	sodium:amino acid symporter activity	molecular function	NAS[10891391]	1
GO:0005886	plasma membrane	cellular component	TAS	839
GO:0015186	L-glutamine transmembrane transporter activity	molecular function	IEA	1
GO:0015804	neutral amino acid transport	biological process	NAS[10891391]	4
GO:0055085	transmembrane transport	biological process	TAS	95
GO:0007268	synaptic transmission	biological process	TAS	103
GO:0030424	axon	cellular component	IEA	37

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SLC38A1 (count: 8)

Gene Symbol	Pathway Count	Pathway List
SLC7A5	7	ion transport; neutral amino acid transmembrane transporter activity; amino acid transport; integral to membrane; plasma membrane; neutral amino acid transport; transmembrane transport;
SLC43A1	6	ion transport; neutral amino acid transmembrane transporter activity; amino acid transport; plasma membrane; neutral amino acid transport; transmembrane transport;
SLC7A10	6	ion transport; neutral amino acid transmembrane transporter activity; amino acid transport; plasma membrane; neutral amino acid transport; transmembrane transport;
SLC3A2	6	ion transport; neutral amino acid transmembrane transporter activity; amino acid transport; integral to membrane; plasma membrane; transmembrane transport;
SLC1A3	6	ion transport; neurotransmitter uptake; integral to membrane; plasma membrane; transmembrane transport; synaptic transmission;
SLC6A19	5	ion transport; neutral amino acid transmembrane transporter activity; amino acid transport; plasma membrane; transmembrane transport;
SLC6A3	5	integral to membrane; plasma membrane; transmembrane transport; synaptic transmission; axon;
SLC6A1	5	integral to membrane; plasma membrane; transmembrane transport; synaptic transmission; axon;

Genes shared at least 2 KEGG pathways with SLC38A1 (count: 0)

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Region: chr12:46576846..46663800 View in gBrowse