ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SKOR1
Previous Symbol	LBXCOR1
Symbol Alias	CORL1, FUSSEL15
Approved Name	SKI family transcriptional corepressor 1
Previous Name	"Lbxcor1 homolog (mouse)"
Name Alias	"transcriptional corepressor CORL1", "functional smad suppressing element 15", "corepressor for LBX1"
Location	15q23
Position	chr15:68112042-68126899, 1
External Links	HGNC: 21326 Entrez Gene: 390598 Ensembl: ENSG00000188779 UCSC: uc031qsn.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 4)

rs_ID	Location	Functional Annotation
rs28670272	chr15:68109907(Fwd)	upstream_gene_variant
rs4776981	chr15:68109474(Fwd)	upstream_gene_variant
rs4776987	chr15:68123915(Fwd)	downstream_gene_variant; intron_variant; upstream_gene_variant
rs4776982	chr15:68114974(Fwd)	intron_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0030425	dendrite	cellular component	IDA[17292623]	51
GO:0006355	regulation of transcription, DNA-dependent	biological process	NAS[17292623]	182
GO:0046332	SMAD binding	molecular function	IPI[17292623]	9
GO:0043025	neuronal cell body	cellular component	IDA[17292623]	56
GO:0005667	transcription factor complex	cellular component	IEA	52
GO:0000166	nucleotide binding	molecular function	IEA	83
GO:0005737	cytoplasm	cellular component	IBA	781
GO:0030514	negative regulation of BMP signaling pathway	biological process	IDA[17292623]	2
GO:0006351	transcription, DNA-dependent	biological process	IEA	281
GO:0003714	transcription corepressor activity	molecular function	IEA	33
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	biological process	IBA	16
GO:0005634	nucleus	cellular component	IBA; NAS[17292623]	877
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	biological process	IBA	90

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SKOR1 (count: 9)

Gene Symbol	Pathway Count	Pathway List
STRN3	5	dendrite; neuronal cell body; cytoplasm; nucleus; negative regulation of transcription from RNA polymerase II promoter;
PSPC1	5	regulation of transcription, DNA-dependent; nucleotide binding; cytoplasm; transcription, DNA-dependent; nucleus;
TFEB	5	regulation of transcription, DNA-dependent; transcription factor complex; cytoplasm; transcription, DNA-dependent; nucleus;
SCAI	5	regulation of transcription, DNA-dependent; cytoplasm; transcription, DNA-dependent; transcription corepressor activity; nucleus;
CREBBP	5	regulation of transcription, DNA-dependent; transcription factor complex; cytoplasm; nucleus; negative regulation of transcription from RNA polymerase II promoter;
TRIM22	5	regulation of transcription, DNA-dependent; cytoplasm; transcription, DNA-dependent; transcription corepressor activity; nucleus;
BCL11A	5	regulation of transcription, DNA-dependent; cytoplasm; transcription, DNA-dependent; transcription corepressor activity; nucleus;
LPIN1	5	transcription factor complex; cytoplasm; transcription, DNA-dependent; nucleus; negative regulation of transcription from RNA polymerase II promoter;
NEDD4L	5	cytoplasm; transcription, DNA-dependent; negative regulation of transforming growth factor beta receptor signaling pathway; nucleus; negative regulation of transcription from RNA polymerase II promoter;

Genes shared at least 2 KEGG pathways with SKOR1 (count: 0)

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Region: chr15:68112042..68126899 View in gBrowse