ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SC5D
Previous Symbol	SC5DL
Approved Name	sterol-C5-desaturase
Previous Name	"sterol-C5-desaturase (fungal ERG3, delta-5-desaturase)-like", "sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like", "sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like"
Name Alias	"lathosterol oxidase"
Location	11q23.3
Position	chr11:121163162-121179403, 1
External Links	HGNC: 10547 Entrez Gene: 6309 Ensembl: ENSG00000109929
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006629	lipid metabolic process	biological process	TAS[8976377]	51
GO:0000248	C-5 sterol desaturase activity	molecular function	IEA	2
GO:0016021	integral to membrane	cellular component	IEA	932
GO:0005789	endoplasmic reticulum membrane	cellular component	TAS	159
GO:0006695	cholesterol biosynthetic process	biological process	TAS	8
GO:0005506	iron ion binding	molecular function	IEA	26
GO:0050046	lathosterol oxidase activity	molecular function	IEA	1
GO:0033490	cholesterol biosynthetic process via lathosterol	biological process	IEA	1
GO:0006633	fatty acid biosynthetic process	biological process	IEA	16
GO:0044281	small molecule metabolic process	biological process	TAS	270

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SC5D (count: 1)

Gene Symbol	Pathway Count	Pathway List
FADS1	5	C-5 sterol desaturase activity; integral to membrane; endoplasmic reticulum membrane; iron ion binding; small molecule metabolic process;

Genes shared at least 2 KEGG pathways with SC5D (count: 0)

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Region: chr11:121163162..121179403 View in gBrowse