ADHDgene Database

Gene Report

Basic Info

Approved Symbol	REXO1L1
Symbol Alias	GOR
Approved Name	REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1
Location	8q21.2
Position	chr8:86568695-86575726, -
External Links	HGNC: 24660 Entrez Gene: 254958 Ensembl: ENSG00000205176 UCSC: uc003ydl.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_6	chr8:85438801-88424995 (NCBI Build 36.1 (hg18))	2935186	8q21.2-8q21.3	Loss	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 4)

ID	Name	Type	No. of Genes in ADHDgene
GO:0003676	nucleic acid binding	Molecular Function	41
GO:0004527	exonuclease activity	Molecular Function	5
GO:0005634	nucleus	Cellular Component	770
GO:0005737	cytoplasm	Cellular Component	690

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03008	Ribosome biogenesis in eukaryotes	12	Ribosomes are the cellular factories responsible for making ...... Ribosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It requires hundreds of factors not present in the mature particle. In the absence of these proteins, ribosome biogenesis is stalled and cell growth is terminated even under optimal growth conditions. The primary pre-rRNA transcript is assembled into the 90S pre-ribosome, which contains both 40S and 60S assembly factors. Within this complex, the pre-rRNA is cleaved. pre-60S ribosomes are subjected to several sequential processing steps in the nucleoplasm involving numerous assembly intermediates before it is exported to the cytoplasm and matured into the 60S ribosomal subunit. The pre-40S ribosome is matured to the small ribosomal subunit in the cytoplasm by cleavage. More...

Genes shared at least 5 GO terms with REXO1L1 (count: 0)

Genes shared at least 2 KEGG pathways with REXO1L1 (count: 0)

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Region: chr8:86568695..86575726 View in gBrowse