ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NUDT3
Symbol Alias	DIPP
Approved Name	nudix (nucleoside diphosphate linked moiety X)-type motif 3
Location	6p21.2
Position	chr6:34247456-34360451, -1
External Links	HGNC: 8050 Entrez Gene: 11165 Ensembl: ENSG00000112664
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Albayrak O., 2013	SNP rs206936 of NUDT3 gene is associated with an increased risk for ADHD.	Significant

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs206936	chr6:34302869(Fwd)	intron_variant	1(1/0/0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0052840	inositol diphosphate tetrakisphosphate diphosphatase activity	molecular function	IEA	1
GO:0005737	cytoplasm	cellular component	IEA	781
GO:0052844	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity	molecular function	IEA	1
GO:0052846	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity	molecular function	IEA	1
GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity	molecular function	IDA[10585413]	1
GO:0052845	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity	molecular function	IEA	1
GO:0000287	magnesium ion binding	molecular function	IDA[19585659]	30
GO:0052847	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	molecular function	IEA	1
GO:0052848	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	molecular function	IEA	1
GO:0071544	diphosphoinositol polyphosphate catabolic process	biological process	IDA[10585413]	1
GO:0007267	cell-cell signaling	biological process	TAS[10419486]	41
GO:0015961	diadenosine polyphosphate catabolic process	biological process	TAS[10419486]	1
GO:0052843	inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity	molecular function	IEA	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NUDT3 (count: 0)

Genes shared at least 2 KEGG pathways with NUDT3 (count: 0)

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Region: chr6:34247456..34360451 View in gBrowse