ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GGA2
Symbol Alias	VEAR, KIAA1080
Approved Name	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Location	16p12
Position	chr16:23474863-23521815, -
External Links	HGNC: 16064 Entrez Gene: 23062 Ensembl: ENSG00000103365 UCSC: uc002dlq.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16p12.3-12.2	chr16:16800000-24200000	1 (1/0/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005515	protein binding	Molecular Function	IPI[12429846]	910
GO:0030306	ADP-ribosylation factor binding	Molecular Function	IDA[10749927]	1
GO:0044431	Golgi apparatus part	Cellular Component		1
GO:0030131	clathrin adaptor complex	Cellular Component		2
GO:0030136	clathrin-coated vesicle	Cellular Component	IDA[19478182]	9
GO:0010008	endosome membrane	Cellular Component		27
GO:0016192	vesicle-mediated transport	Biological Process		28
GO:0005802	trans-Golgi network	Cellular Component	IDA[10749927]	28
GO:0006886	intracellular protein transport	Biological Process	NAS[10749927]	43

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04142	Lysosome	19	Lysosomes are membrane-delimited organelles in animal cells ...... Lysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than 40 hydrolases in an acidic environment (pH of about 5). After synthesis in the ER, lysosomal enzymes are decorated with mannose-6-phosphate residues, which are recognized by mannose-6-phosphate receptors in the trans-Golgi network. They are packaged into clathrin-coated vesicles and are transported to late endosomes. Substances for digestion are acquired by the lysosomes via a series of processes including endocytosis, phagocytosis, and autophagy. More...

Genes shared at least 5 GO terms with GGA2 (count: 0)

Genes shared at least 2 KEGG pathways with GGA2 (count: 0)

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Region: chr16:23474863..23521815 View in gBrowse