ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol BRE
Symbol Alias BRCC45, BRCC4
Approved Name brain and reproductive organ-expressed (TNFRSF1A modulator)
Name Alias "BRCA1/BRCA2-containing complex, subunit 4"
Location 2p23
Position chr2:28112808-28561768, 1
External Links HGNC: 1106
Entrez Gene: 9577
Ensembl: ENSG00000158019
UCSC: uc002rls.3
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 1)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Schimmelmann, B. G.,2013 We found no significant association of childhood ADHD with single BD risk alleles surviving adjustment for multiple testing. Yet, association signal with nominal p value is below 5%. Only for the two coding SNPs in NCAN and BRE, we observed a consistent risk allele pattern across both control group comparisons. Significant

Gene related SNPs (count: 15)

Literature-origin SNPs (count: 1)

LD-proxies (count: 14)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 17)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 17)

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with BRE (count: 13)

Genes shared at least 2 KEGG pathways with BRE (count: 0)

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Region: chr2:28112808..28561768 View in gBrowse
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