Meta-analysis Report
Basic Info
| Reference |
Sun H, 201323907791
|
| Citation |
Sun H, Yuan F, Shen X, Xiong G, Wu J (2014) Role of COMT in ADHD: a Systematic Meta-Analysis. Mol Neurobiol 49: 251-61. doi: 10.1007/s12035-013-8516-5
|
| Study Type |
Candidate association study |
| Summary |
Considerable evidence above reveals that the COMT Val/Met SNP is germane to ADHD and becomes one of the most popular SNPs in ADHD. However, the negative result of the meta-analysis on involvement of the COMT Val/Met polymorphism in increasing the risk for ADHD cannot be considered definitive. |
Detail Info
| Samples |
A total of 18 studies with 2659 subjects |
| Statistic Method |
The meta-analysis procedures were performed using the metafor package in R |
| Basic Result |
The results of pooled analysis did not support an association between the Val/Met SNP and ADHD (pooled OR=1.02, 95 % CI 0.92-1.13, P=0.7267). |
SNPs reported by this study: 1
| SNP |
Allele Change |
Risk Allele |
Statistical Values |
Author Comments |
Result of Statistical Analysis |
| rs4680 |
|
|
pooled OR=1.02, 95 % CI 0.92-1.13, P=0.7267 |
SNP indicated no significant association with ADHD
SNP indicated no significant association with ADHD
|
Non-significant
|
Genes reported by this study: 1
| Gene |
Statistical Values/Author Comments |
Result of Statistical Analysis |
| COMT |
No significant or Trend associated SNP was mapped in this ge......
No significant or Trend associated SNP was mapped in this gene.
More...
|
Non-significant
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