ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Study Report

Basic Info
Reference Comings DE, 19968873217
Citation Comings D. E., Gade R., Muhleman D., Chiu C., Wu S., To M., Spence M., Dietz G., Winn-Deen E., Rosenthal R. J., Lesieur H. R., Rugle L., Sverd J., Ferry L., Johnson J. P. and MacMurray J. P. (1996) "Exon and intron variants in the human tryptophan 2,3-dioxygenase gene: potential association with Tourette syndrome, substance abuse and other disorders." Pharmacogenetics, 6(4): 307-18.
Study Design case-control
Study Type Candidate-gene association study
Sample Size 113 ADHD patients and 141 controls for intron 6 G->A TDO2 polymorphism; 108 ADHD patients and 197 controls for intron 6 G->T TDO2 polymorphism; 96 ADHD patients and 135 controls for intron 6 either G->A or G->T TDO2 polymorphism
Predominant Ethnicity Caucasian
Population USA

Detail Info

Other variant reported by this study (count: 4)

Genes reported by this study (count: 1)