ADHDgene Database

SNP Report

Basic Info

Name	rs821633 dbSNP Ensembl
Location	chr1:232148933(Fwd)
Variant Alleles	T/C
Ancestral Allele	C
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000422590; ENST00000427560; ENST00000535983; ENST00000537876) intron_variant(ENST00000366637; ENST00000439617)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Jacobsen, K. K.,2013			chi-square tests P-value=0.57 (OR=1.05;95%CI=0.89-1.23) chi-square tests P-value=0.57 (OR=1.05;95%CI=0.89-1.23)	This SNP was not significant associated with ADHD This SNP was not significant associated with ADHD	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DISC1	disrupted in schizophrenia 1	1q42.1	1(1/0/0)

SNPs in LD with rs821633 (count: 13) View in gBrowse (chr1:232148933..232153031 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs821645	intron_variant	1.0[CEU]; 1.0[CHB]; 0.953[JPT]
rs821637	downstream_gene_variant; intron_variant	0.958[CEU]; 1.0[CHB]; 0.953[JPT]
rs821642	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.957[JPT]
rs821641	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.957[JPT]
rs821643	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.898[JPT]
rs821634	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.953[JPT]; 0.864[YRI]
rs821639	downstream_gene_variant; intron_variant	0.955[CEU]
rs821647	intron_variant	0.957[CEU]
rs821648	intron_variant	1.0[CEU]; 1.0[CHB]; 0.956[JPT]
rs821638	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.957[JPT]
rs821635	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.957[JPT]
rs821644	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.956[JPT]
rs821640	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.957[JPT]