ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs6314 dbSNP Ensembl
Location chr13:47409034(Fwd)
Variant Alleles G/A
Ancestral Allele G
Functional Annotation missense_variant.
Polyphen Annotation: benign(ENST00000378688; ENST00000542664; ENST00000543956)
SIFT Annotation: tolerated(ENST00000378688; ENST00000542664; ENST00000543956)
Consequence to Transcript missense_variant(ENST00000378688; ENST00000542664; ENST00000543956)
No. of Studies 4 (significant: 0; non-significant: 4; trend: 0)
Source Literature-origin

SNP related studies (count: 4)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Brookes K, 2006 A/G UNPHASED TDT P-value=0.947; WHAP TDT P-value=0.667 UNPHASED TDT P-value=0.947; WHAP TDT P-value=0.667 no significant association was observed no significant association was observed Non-significant
Gizer IR, 2009 Meta-analysis model: Random: OR=1.05, 95% CI=0.82-1.34, P-va...... Meta-analysis model: Random: OR=1.05, 95% CI=0.82-1.34, P-value=0.343; Q-statistic: P-value=0.121, I2=42 More... no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More... Non-significant
Heiser P, 2007 C/T allelic PDT P-value=0.50 allelic PDT P-value=0.50 showed no statistically significant preferential transmissio...... showed no statistically significant preferential transmission of any allele More... Non-significant
Bobb AJ, 2005 allelic TDT P-value=0.49, OR=1.19 in case-control analysis; ...... allelic TDT P-value=0.49, OR=1.19 in case-control analysis; allelic TDT P-value=0.3, RR=0.64 in family-based analysis More... non-significant association non-significant association Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs6314 (count: 4) View in gBrowse (chr13:47406628..47409034 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)