ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs6280 dbSNP Ensembl
Location chr3:113890815(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation missense_variant.
Polyphen Annotation: benign(ENST00000295881; ENST00000383673; ENST00000460779; ENST00000467632)
SIFT Annotation: tolerated(ENST00000295881; ENST00000383673; ENST00000460779; ENST00000467632)
Consequence to Transcript missense_variant(ENST00000295881; ENST00000383673; ENST00000460779; ENST00000467632)
No. of Studies 2 (significant: 0; non-significant: 2; trend: 0)
Source Literature-origin

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Kirley A, 2002 HHRR: P-value=0.56 (RR=1.07, OR=1.15); TDT: P-value=0.893 (O...... HHRR: P-value=0.56 (RR=1.07, OR=1.15); TDT: P-value=0.893 (OR=1.07); TDT by presence of family history: P-value=1 (OR[95%CI]=1.22[0.31-4.80]); TDT of Paternal and Maternal transmissions: P-value=0.976 (OR[95%CI]=1.02[0.30-3.44]) More... no significant differences between transmitted and non-trans...... no significant differences between transmitted and non-transmitted alleles More... Non-significant
Gizer IR, 2009 Meta-analysis model: Fixed: OR=1.07, 95% CI=0.95-1.21, two-t...... Meta-analysis model: Fixed: OR=1.07, 95% CI=0.95-1.21, two-tailed P-value=0.268; Q-statistic: P-value=0.952, I2=0 More... no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More... Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs6280 (count: 21) View in gBrowse (chr3:113879404..113937999 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 21)