ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs6090384 dbSNP Ensembl
Location chr20:61990874(Fwd)
Variant Alleles T/C
Ancestral Allele C
Functional Annotation intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000370263; ENST00000463705; ENST00000467563; ENST00000498043)
nc_transcript_variant(ENST00000463705; ENST00000467563)
NMD_transcript_variant(ENST00000498043)
upstream_gene_variant(ENST00000370257)
No. of Studies 4 (significant: 0; non-significant: 4; trend: 0)
Source Literature-origin

SNP related studies (count: 4)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Bobb AJ, 2005 allelic TDT P-value=0.47, OR=1.23 in case-control analysis; ...... allelic TDT P-value=0.47, OR=1.23 in case-control analysis; allelic TDT P-value=0.83, RR=1.1 in family-based analysis More... non-significant association non-significant association Non-significant
Gizer IR, 2009 Meta-analysis model: Random: OR=1.28, 95% CI=0.89-1.84, P-va...... Meta-analysis model: Random: OR=1.28, 95% CI=0.89-1.84, P-value=0.093; Q-statistic: P-value=0.271, I2=23 More... The results of this meta-analysis also suggested a trend tow...... The results of this meta-analysis also suggested a trend towards association with childhood ADHD with no significant evidence of heterogeneity in effect sizes across studies. Sensitivity analyses indicated this association reached significance after removing the Brookes et al. (2006a) study, though removing any of the other studies reduced the trend to non-significance. It is likely that the fluctuations in the significance of this association observed in the sensitivity analyses were influenced by the small number of studies included in the meta-analysis. More... Non-significant
Brookes K, 2006 A/G UNPHASED TDT P-value=0.763; WHAP TDT P-value=0.575 UNPHASED TDT P-value=0.763; WHAP TDT P-value=0.575 no significant association was observed no significant association was observed Non-significant
Lee J, 2008 G/A P-value=0.446, X2 (1df)=0.581 in all subtypes; P-...... P-value=0.446, X2 (1df)=0.581 in all subtypes; P-value=0.782, X2 (1df)=0.077 in inattentive subtype; P-value=0.819, X2 (1df)=0.053 in combined subtype More... no significant evidence of association no significant evidence of association Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs6090384 (count: 0) View in gBrowse (chr20:61990874..61990874 )