ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs5906754 dbSNP Ensembl
Location chrX:49060227(Fwd)
Variant Alleles T/C
Ancestral Allele C
Functional Annotation downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000323022; ENST00000376251; ENST00000376265; ENST00000433499)
upstream_gene_variant(ENST00000263233; ENST00000376303; ENST00000466635; ENST00000469389; ENST00000472598; ENST00000472737; ENST00000479808; ENST00000494396; ENST00000538567; ENST00000583131)
No. of Studies 3 (significant: 3; non-significant: 0; trend: 0)
Source Literature-origin

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Liu, L.,2013 TDT tests for family-based:Empirical P-value=0.0151(Associat...... TDT tests for family-based:Empirical P-value=0.0151(Associated phenotype:Male ADHD-I),Empirical P-value=0.0377(Associated phenotype:ADHD-I);Chi-square tests for case-control:Empirical P-value=0.0217(Associated phenotype:Female ADHD), X2=5.026,Empirical P-value=0.0676(Associated phenotype:Female ADHD-I) More... The TDT analysis of this SNP showed biased transmission The TDT analysis of this SNP showed biased transmission Significant
Guan L, 2009 single SNP association analyses: Nominal P-value=0.045, Empi...... single SNP association analyses: Nominal P-value=0.045, Empirical P-value=0.048 for ADHD-I More... non-significant for ADHD, but achieve nominal and empirical ...... non-significant for ADHD, but achieve nominal and empirical significance for ADHD-I More... Significant
Brookes K, 2006 A/G UNPHASED TDT P-value=0.0453 UNPHASED TDT P-value=0.0453 significant association was observed in UNPHASED analysis significant association was observed in UNPHASED analysis Significant

SNP related genes (count: 3)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 2)


SNPs in LD with rs5906754 (count: 13) View in gBrowse (chrX:49051624..49100691 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 13)