ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs2298122 dbSNP Ensembl
Location	chr10:135141572(Fwd)
Variant Alleles	G/T
Ancestral Allele	G
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000252939; ENST00000368554; ENST00000368555; ENST00000368556; ENST00000368558) upstream_gene_variant(ENST00000467433; ENST00000467611; ENST00000605518)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Laurin N, 2005	A/C		allelic ETDT P-value=0.124, X²(1df)=2.368 allelic ETDT P-value=0.124, X²(1df)=2.368	TDT statistic was not significant TDT statistic was not significant	Non-significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
CALY	calcyon neuron-specific vesicular protein	10q26.3	2(1/1/0)

Genes from other sources (count: 1)

Approved Symbol	Approved Name	Location
ZNF511	zinc finger protein 511	10q26.3

SNPs in LD with rs2298122 (count: 16) View in gBrowse (chr10:135071004..135141572 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 16)

rs_ID	Functional Annotation	r²[population]
rs11101690	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.826[TSI]; 1.0[CHB]; 1.0[CHD]; 0.904[JPT]
rs3008349	downstream_gene_variant; intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.904[JPT]
rs3008354	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.851[TSI]; 1.0[CHB]; 1.0[CHD]; 0.904[JPT]
rs2298120	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant; synonymous_variant; upstream_gene_variant	0.852[CHD]
rs2105341	downstream_gene_variant; intron_variant	1.0[CHB]; 1.0[JPT]
rs2995335	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.904[JPT]
rs2275724	downstream_gene_variant; intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.884[TSI]; 0.812[JPT]; 0.931[GIH]
rs2230576	3_prime_UTR_variant; nc_transcript_variant; non_coding_exon_variant	0.831[GIH]
rs3008352	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]; 1.0[CHB]; 1.0[CHD]; 0.904[JPT]; 0.965[GIH]; 0.842[MEX]
rs3008336	intron_variant; NMD_transcript_variant; upstream_gene_variant	0.97[TSI]; 0.812[JPT]; 0.965[GIH]
rs7085530	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.896[JPT]
rs11101684	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]
rs7912335	downstream_gene_variant	0.864[GIH]
rs12250582	downstream_gene_variant; intron_variant; upstream_gene_variant	0.823[TSI]; 1.0[CHD]
rs2995332	3_prime_UTR_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.854[TSI]; 1.0[CHB]; 1.0[CHD]; 0.904[JPT]
rs3008348	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.904[JPT]