ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs2293945 dbSNP Ensembl
Location chrX:49047619(Fwd)
Variant Alleles T/C
Ancestral Allele C
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000479808)
downstream_gene_variant(ENST00000466635; ENST00000469389)
intron_variant(ENST00000263233; ENST00000376303; ENST00000472598; ENST00000538567)
NMD_transcript_variant(ENST00000376303)
upstream_gene_variant(ENST00000376310; ENST00000376317; ENST00000417014; ENST00000538114)
No. of Studies 2 (significant: 2; non-significant: 0; trend: 0)
Source Literature-origin

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Liu, L.,2013 TDT tests for family-based:Empirical P-value=0.0294(Associat...... TDT tests for family-based:Empirical P-value=0.0294(Associated phenotype:Male ADHD-I),Empirical P-value=0.0794(Associated phenotype:ADHD-I);Chi-square tests for case-control:Empirical P-value=0.0522(Associated phenotype:Female ADHD), X2=3.750 More... The TDT analysis of this SNP showed biased transmission The TDT analysis of this SNP showed biased transmission Significant
Brookes KJ, 2005 (b) MRM P-value=0.03, Case-control P-value=0.09, TDT P-value=0.0...... MRM P-value=0.03, Case-control P-value=0.09, TDT P-value=0.005 More... remained significant following case-control and TDT analysis...... remained significant following case-control and TDT analysis of the individually genotyped data More... Significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 1)


SNPs in LD with rs2293945 (count: 13) View in gBrowse (chrX:49047619..49100691 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 13)