ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs1799971 dbSNP Ensembl
Location chr6:154360797(Fwd)
Variant Alleles A/G
Ancestral Allele A
Functional Annotation intron_variant; missense_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant.
Polyphen Annotation: benign(ENST00000229768; ENST00000330432; ENST00000337049; ENST00000360422; ENST00000428397; ENST00000434900; ENST00000519083; ENST00000522739; ENST00000524163) | possibly damaging(ENST00000414028; ENST00000419506; ENST00000435918; ENST00000452687) | probably damaging(ENST00000520282; ENST00000524150; ENST00000519083; ENST00000522739; ENST00000524150)
SIFT Annotation: deleterious(ENST00000229768; ENST00000330432; ENST00000337049; ENST00000360422; ENST00000428397; ENST00000434900; ENST00000519083' target='_blank'> ENST00000519083; ENST00000522739' target='_blank'> ENST00000522739; ENST00000524163; ENST00000414028; ENST00000419506; ENST00000435918; ENST00000452687; ENST00000520282; ENST00000524150' target='_blank'> ENST00000524150; ENST00000519083' target='_blank'> ENST00000519083; ENST00000522739' target='_blank'> ENST00000522739; ENST00000524150' target='_blank'> ENST00000524150)
Consequence to Transcript intron_variant(ENST00000518759; ENST00000520708)
missense_variant(ENST00000229768; ENST00000330432; ENST00000337049; ENST00000360422; ENST00000428397; ENST00000434900; ENST00000519083; ENST00000522739; ENST00000524163; ENST00000414028; ENST00000419506; ENST00000435918; ENST00000452687; ENST00000520282; ENST00000524150)
nc_transcript_variant(ENST00000523520)
NMD_transcript_variant(ENST00000519083; ENST00000522739; ENST00000524150)
non_coding_exon_variant(ENST00000523520)
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Carpentier, P. J., 2012 A>G G genotypic P-value=0.006, adj OR=1.71, 95%CI=1.17-2.50; P-val...... genotypic P-value=0.006, adj OR=1.71, 95%CI=1.17-2.50; P-value=0.50, adj OR=1.12, 95%CI=0.81-1.54 with gender as the covariate More... After the Bonferroni correction, a significant association w...... After the Bonferroni correction, a significant association with disease was found for the DBH (OR 1.73;CI1.15-2.59; P=0.008)and the OPRM1 (OR 1.71;CI1.17-2.50; P=0.006) risk genotypes. The covariate Gender had no significant effect. More... Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs1799971 (count: 19) View in gBrowse (chr6:154312386..154418414 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 19)