ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs1137070 dbSNP Ensembl
Location chrX:43603391(Fwd)
Variant Alleles T/C
Ancestral Allele C
Functional Annotation nc_transcript_variant; non_coding_exon_variant; synonymous_variant.
Consequence to Transcript nc_transcript_variant(ENST00000490604)
non_coding_exon_variant(ENST00000490604)
synonymous_variant(ENST00000338702; ENST00000542639)
No. of Studies 4 (significant: 3; non-significant: 1; trend: 0)
Source Literature-origin

SNP related studies (count: 4)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Liu, L., 2011 T TDT P-value=0.633 in all ADHD, P-value=0.268 in male ADHD, P...... TDT P-value=0.633 in all ADHD, P-value=0.268 in male ADHD, P-value=0.230 in female ADHD; P-value=0.752 in all ADHD-I, P-value=0.251 in male ADHD-I, P-value=0.145 in female ADHD-I; P-value=0.614 in all ADHD-C, P-value=0.732 in male ADHD-C, P-value=0.631 in female ADHD-C; Nominal P-value=0.008, Empirical P-value=0.019, X2=7 in ADHD-HI Trios; Nominal P-value=0.014, Empirical P-value=0.029, X2=6; Logistic Regression, P-value=0.782, OR=0.985; P-value<0.001, OR=0.983 after controlling for potentially confounding factors like age; P-value<0.001, OR=0.221 after controlling for potentially confounding factors like gender More... No biased transmission of any allele of any of the five eval...... No biased transmission of any allele of any of the five evaluated polymorphisms was observed for the entire sample of ADHD, ADHD-I, or ADHD-C. We only found biased transmission of these SNPs in the ADHD-HI subgroup. No association was found for ADHD females or subtypes. The results showed that there was no different genotype distribution of any SNP after controlling for potentially confounding factors including gender and age. More... Significant
Hawi, Z., 2012 C:T C P-value=0.6188, X2=0.24, OR=1.1, 95% CI=0.74-1.63 P-value=0.6188, X2=0.24, OR=1.1, 95% CI=0.74-1.63 The marker did not show significant association with ADHD. The marker did not show significant association with ADHD. Non-significant
Brookes K, 2006 A/G UNPHASED TDT P-value=0.0195 UNPHASED TDT P-value=0.0195 significant association was observed in UNPHASED analysis significant association was observed in UNPHASED analysis Significant
Guan L, 2009 single SNP association analyses: Nominal P-value=0.012, Empi...... single SNP association analyses: Nominal P-value=0.012, Empirical P-value=0.017 for ADHD; Nominal P-value=0.018, Empirical P-value=0.034 for ADHD-I More... achieve nominal and empirical significance for ADHD and ADHD...... achieve nominal and empirical significance for ADHD and ADHD-I More... Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs1137070 (count: 34) View in gBrowse (chrX:43438662..43612708 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 34)