ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs10421632 dbSNP Ensembl
Location	chr19:57764770(Fwd)
Variant Alleles	G/A
Functional Annotation	missense_variant. Polyphen Annotation: benign(ENST00000354309; ENST00000414468; ENST00000535550) SIFT Annotation: tolerated(ENST00000354309; ENST00000414468; ENST00000535550)
Consequence to Transcript	missense_variant(ENST00000354309; ENST00000414468; ENST00000535550)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lasky-Su J, 2008			P-value=9.68E-06 under Additive model for HI symptom count P-value=9.68E-06 under Additive model for HI symptom count	association finding with P-value association finding with P-value	Trend

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ZNF805	zinc finger protein 805	19q13.43	1(0/0/1)

Genes from other sources (count: 0)

SNPs in LD with rs10421632 (count: 27) View in gBrowse (chr19:57717532..57779521 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 27)

rs_ID	Functional Annotation	r²[population]
rs11667407	intron_variant	1.0[CEU]; 1.0[CHB]; 0.907[JPT]; 1.0[YRI]
rs11879048	downstream_gene_variant	0.862[CHB]
rs8106734	intron_variant	1.0[CEU]; 1.0[TSI]; 1.0[ASW]; 0.93[CHB]; 0.922[CHD]; 0.933[JPT]; 1.0[GIH]; 0.909[LWK]; 1.0[MEX]; 0.943[MKK]; 1.0[YRI]
rs10414184	intron_variant; nc_transcript_variant	0.839[YRI]
rs4801452	downstream_gene_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]; 1.0[ASW]; 0.933[CHB]; 1.0[CHD]; 0.933[JPT]; 1.0[GIH]; 0.969[LWK]; 0.953[MEX]; 1.0[MKK]; 1.0[YRI]
rs8111661	intron_variant	0.862[CHB]; 0.883[CHD]; 0.863[JPT]; 0.846[GIH]; 0.863[MEX]
rs10412975	downstream_gene_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]; 0.933[ASW]; 0.933[CHB]; 0.962[CHD]; 0.862[JPT]; 0.932[GIH]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 0.951[YRI]
rs7248000	intron_variant	1.0[CEU]; 1.0[TSI]; 1.0[ASW]; 1.0[CHB]; 0.962[CHD]; 0.933[JPT]; 1.0[GIH]; 0.969[LWK]; 1.0[MEX]; 0.943[MKK]; 1.0[YRI]
rs7252399	downstream_gene_variant; upstream_gene_variant	0.862[CHB]; 0.845[CHD]; 0.863[JPT]
rs3746231	5_prime_UTR_variant; missense_variant	1.0[CEU]; 1.0[CHB]; 0.861[JPT]; 0.865[YRI]
rs10408146		0.862[CHB]; 0.844[CHD]
rs3826970	downstream_gene_variant	0.901[YRI]
rs10427146	intron_variant	1.0[CEU]; 1.0[CHB]; 0.855[JPT]
rs6510050		0.862[CHB]; 0.845[CHD]
rs10414299	downstream_gene_variant	0.862[CHB]
rs10406954	intron_variant	0.902[YRI]
rs12460702	intron_variant	0.862[CHB]
rs10418480	intron_variant	1.0[CEU]; 1.0[TSI]; 0.819[ASW]; 1.0[CHB]; 1.0[CHD]; 0.863[JPT]; 0.978[GIH]; 0.954[MEX]
rs10413037	upstream_gene_variant	1.0[CEU]; 1.0[TSI]; 0.933[ASW]; 0.892[CHD]; 0.801[JPT]; 1.0[GIH]; 0.969[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[YRI]
rs11084492	intron_variant	1.0[CEU]; 1.0[CHB]; 0.848[JPT]
rs12460381	intron_variant	0.862[CHB]
rs10415216	upstream_gene_variant	0.902[YRI]
rs10405008	intron_variant	0.886[CEU]; 0.977[TSI]; 0.927[CHB]; 0.961[CHD]; 0.863[JPT]; 0.955[GIH]; 1.0[MEX]
rs10415639	upstream_gene_variant	0.854[YRI]
rs10413671	intron_variant	0.951[CEU]; 1.0[CHB]; 0.923[JPT]; 1.0[YRI]
rs13345715		0.862[CHB]
rs7259978	intron_variant	1.0[CEU]; 1.0[CHB]; 0.863[JPT]